Detailed information NTG1086555

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ACLF6N_RS13570
• Genome accession: NZ_CP177279
• Coordinates: 2494757..2497087 (-)
• Length: 776 a.a.
• NCBI ID: WP_046160607.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain KFRI-P74
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2489757..2502087

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLF6N_RS13535 (ACLF6N_13535)	yqxA	2490095..2490433 (-)	339	WP_046160606.1	YqxA family protein	-
ACLF6N_RS13540 (ACLF6N_13540)	spoIIP	2490450..2491655 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
ACLF6N_RS13545 (ACLF6N_13545)	gpr	2491718..2492824 (-)	1107	WP_014480309.1	GPR endopeptidase	-
ACLF6N_RS13550 (ACLF6N_13550)	rpsT	2493028..2493294 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
ACLF6N_RS13555 (ACLF6N_13555)	holA	2493309..2494352 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
ACLF6N_RS13560 (ACLF6N_13560)	-	2494392..2494505 (-)	114	WP_122060479.1	hypothetical protein	-
ACLF6N_RS13565 (ACLF6N_13565)	yqzM	2494582..2494716 (+)	135	WP_003229983.1	YqzM family protein	-
ACLF6N_RS13570 (ACLF6N_13570)	comEC	2494757..2497087 (-)	2331	WP_046160607.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACLF6N_RS13575 (ACLF6N_13575)	comEB	2497091..2497660 (-)	570	WP_003229978.1	ComE operon protein 2	-
ACLF6N_RS13580 (ACLF6N_13580)	comEA	2497727..2498344 (-)	618	WP_046160608.1	competence protein ComEA	Machinery gene
ACLF6N_RS13585 (ACLF6N_13585)	comER	2498428..2499249 (+)	822	WP_032726195.1	late competence protein ComER	-
ACLF6N_RS13590 (ACLF6N_13590)	yqeM	2499315..2500058 (-)	744	WP_046160609.1	class I SAM-dependent DNA methyltransferase	-
ACLF6N_RS13595 (ACLF6N_13595)	rsfS	2500055..2500411 (-)	357	WP_014480315.1	ribosome silencing factor	-
ACLF6N_RS13600 (ACLF6N_13600)	yqeK	2500429..2500989 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ACLF6N_RS13605 (ACLF6N_13605)	nadD	2500979..2501548 (-)	570	WP_041333756.1	nicotinate-nucleotide adenylyltransferase	-
ACLF6N_RS13610 (ACLF6N_13610)	yhbY	2501560..2501850 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86846.48 Da
• Isoelectric Point: 7.2477

>NTDB_id=1086555 ACLF6N_RS13570 WP_046160607.1 2494757..2497087(-) (comEC) [Bacillus subtilis strain KFRI-P74]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVKTPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFHQVKTSLRQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVEVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAEILLKYHKVKRLVIPKGFVSEPKDEKVLQAAREEGVEIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=1086555 ACLF6N_RS13570 WP_046160607.1 2494757..2497087(-) (comEC) [Bacillus subtilis strain KFRI-P74]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATTCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTTTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGTCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCATCA
GGTTAAAACCTCTTTGAGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTGTATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGAAGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGAGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAGCAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGATTCTGCTGAAGTATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGGCAGCCAGGGAAG
AGGGAGTGGAAATTGAAGAGGTGAAGCGAGGCGATGTGTTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCGGAA
GCACCTGATCCGGCAAGCAAAAATAATTCATCTCTCGTTCTTTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAAGAGGTGATGAACGTGTTTCCGAATATAAAAGCAGATGTGTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGACCAAAA
CGGAACGATCCAATATAGATATAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.711	100	0.987