Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACJWMD_RS07115 Genome accession   NZ_CP177182
Coordinates   1508501..1509727 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain MRD6060     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1503501..1514727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS07085 plsY 1503845..1504486 (+) 642 WP_004182953.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  ACJWMD_RS07090 - 1504604..1504981 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  ACJWMD_RS07095 - 1505056..1505310 (-) 255 WP_004182954.1 DUF1912 family protein -
  ACJWMD_RS07100 mmuM 1505423..1506373 (-) 951 WP_004182955.1 homocysteine S-methyltransferase -
  ACJWMD_RS07105 - 1506386..1507762 (-) 1377 WP_004182956.1 amino acid permease -
  ACJWMD_RS07110 yihA 1507892..1508491 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACJWMD_RS07115 clpX 1508501..1509727 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACJWMD_RS07120 - 1509745..1509915 (-) 171 WP_002886174.1 hypothetical protein -
  ACJWMD_RS07125 - 1509920..1510423 (-) 504 WP_004182957.1 dihydrofolate reductase -
  ACJWMD_RS07130 - 1510532..1511392 (-) 861 WP_004182958.1 thymidylate synthase -
  ACJWMD_RS07135 - 1511863..1513029 (+) 1167 WP_004182959.1 hydroxymethylglutaryl-CoA synthase -
  ACJWMD_RS07140 - 1513031..1514302 (+) 1272 WP_004182960.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=1086023 ACJWMD_RS07115 WP_002890340.1 1508501..1509727(-) (clpX) [Streptococcus salivarius strain MRD6060]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1086023 ACJWMD_RS07115 WP_002890340.1 1508501..1509727(-) (clpX) [Streptococcus salivarius strain MRD6060]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCGAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCTTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACCGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGAAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCTGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGAATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTTTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATCCAAAAATTTGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTGGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTTA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCTGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment