Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACJWMC_RS02960 Genome accession   NZ_CP177181
Coordinates   590218..591444 (+) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain MRD1919     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 585218..596444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS02935 - 585651..586922 (-) 1272 WP_002890330.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ACJWMC_RS02940 - 586924..588090 (-) 1167 WP_037597547.1 hydroxymethylglutaryl-CoA synthase -
  ACJWMC_RS02945 - 588553..589413 (+) 861 WP_002890336.1 thymidylate synthase -
  ACJWMC_RS02950 - 589522..590025 (+) 504 WP_037597549.1 dihydrofolate reductase -
  ACJWMC_RS02955 - 590030..590200 (+) 171 WP_002886174.1 hypothetical protein -
  ACJWMC_RS02960 clpX 590218..591444 (+) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACJWMC_RS02965 yihA 591454..592053 (+) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACJWMC_RS02970 - 592183..593559 (+) 1377 WP_037597551.1 amino acid permease -
  ACJWMC_RS02975 mmuM 593571..594521 (+) 951 WP_037597554.1 homocysteine S-methyltransferase -
  ACJWMC_RS02980 - 594634..594888 (+) 255 WP_002886199.1 DUF1912 family protein -
  ACJWMC_RS02985 - 594963..595340 (+) 378 WP_002890347.1 helix-hairpin-helix domain-containing protein -
  ACJWMC_RS02990 plsY 595457..596098 (-) 642 WP_002890350.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=1085933 ACJWMC_RS02960 WP_002890340.1 590218..591444(+) (clpX) [Streptococcus salivarius strain MRD1919]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1085933 ACJWMC_RS02960 WP_002890340.1 590218..591444(+) (clpX) [Streptococcus salivarius strain MRD1919]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCGAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAGGACCGTGCC
AAACGTGCCTTGGCGGTAGCTGTTTACAATCACTATAAACGTATCAATTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCATTTGCGATTGCGGATGCAACATCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATCGAACGTGCGGAACGTGGTATCATCTATGTTGACGAGATTGATAAGAT
TGCTAAAAAGGGTGAAAATGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATCG
AAGGAACAGTAGCCAGCGTTCCCCCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTTGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCAATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTACCAAACCCTCTTGTCTTATGATGGGGTTGAACTGGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCAATTGAACGTAAGACCGGTGCGCGTGGCCTTCGCTCTATCATTGAGGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACAAAAGAAGCCGTTGACGGCACA
GCTGCTCCAGTTTTGGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment