Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ACJWMC_RS01890 Genome accession   NZ_CP177181
Coordinates   363976..365295 (+) Length   439 a.a.
NCBI ID   WP_002890022.1    Uniprot ID   J7TQ48
Organism   Streptococcus salivarius strain MRD1919     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 358976..370295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS01865 - 359852..360616 (+) 765 WP_002883723.1 ABC transporter ATP-binding protein -
  ACJWMC_RS01870 - 360616..361326 (+) 711 WP_002890015.1 ABC transporter ATP-binding protein -
  ACJWMC_RS01875 - 361461..362120 (+) 660 WP_002890017.1 CBS and ACT domain-containing protein -
  ACJWMC_RS01880 cysK 362267..363193 (-) 927 WP_002890018.1 cysteine synthase A -
  ACJWMC_RS01885 - 363295..363921 (-) 627 WP_002890020.1 YigZ family protein -
  ACJWMC_RS01890 comFA/cflA 363976..365295 (+) 1320 WP_002890022.1 DEAD/DEAH box helicase Machinery gene
  ACJWMC_RS01895 - 365276..365938 (+) 663 WP_002890024.1 ComF family protein -
  ACJWMC_RS01900 hpf 366016..366183 (+) 168 Protein_336 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50709.99 Da        Isoelectric Point: 9.7608

>NTDB_id=1085927 ACJWMC_RS01890 WP_002890022.1 363976..365295(+) (comFA/cflA) [Streptococcus salivarius strain MRD1919]
MVPKEYYGRLFTKEQLPVDYHPEALTLESMIKVDKQLRCKRCYSRIEEDWQLPGGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWFGELTPYQAKVSEKLLRTYQKQKDSLVHAVTGAGKTEMIYNIVAYVLENKGHVAIASPRVDVCRELFLR
MKRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQSFDLVIVDEVDAYPFVGNVMLNHAVVQAKTQTGRFIYLTATST
LSLEEQVRLGPLEKHHLARRFHGNPLVLPKFFWQGRLQKSLTRDKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSAM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1085927 ACJWMC_RS01890 WP_002890022.1 363976..365295(+) (comFA/cflA) [Streptococcus salivarius strain MRD1919]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAGCAGTTGCCAGTGGACTATCACCCAGAGGCTTTAACATT
AGAAAGTATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCGGATAGAGGAAGATTGGCAATTACCGG
GAGGTCAGTATTATTGTAGAGCATGTATTGTCTTTGGTAGAAACCAAGAAGGAAAAGAACTATATTATTTTCCTTCCAAA
ACATCAGAAATTGAATTTCCTGTTTTGAAGTGGTTTGGAGAATTGACTCCCTATCAAGCTAAGGTCTCAGAGAAACTTTT
GAGAACTTATCAAAAACAGAAAGATAGTCTCGTACATGCTGTGACCGGTGCTGGTAAGACAGAAATGATTTATAACATCG
TTGCCTATGTTCTTGAAAATAAAGGTCATGTAGCTATCGCAAGTCCTAGGGTTGATGTTTGTCGAGAATTATTTCTACGT
ATGAAGAGGGATTTTACTTGTAGTATTTCCCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACACATCAACTACTAAAGTTTTACCAGAGTTTTGACTTAGTTATTGTAGATGAAGTAGACGCATATCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTAGTACAAGCGAAGACCCAAACCGGTCGATTTATTTACTTAACAGCGACTTCAACA
TTATCTTTAGAAGAGCAAGTTCGACTTGGGCCTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTTCTGGCAGGGCAGATTACAAAAATCTCTGACAAGAGACAAGCTTCCAAGACCTCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAATTTCCTCTATTAATCTTCTTTCCAAATATAGCGATAGGTGAAAAGTTTACAAGTATT
CTACAAAAATATCTTCCAGATGAAAAAATGGCCTTTGTTTCCTCAAAAAGCGAGGAGCGTTCAACTATCGTAGAGAAGTT
CCGAAAAAAAGAACTGTCTATCTTAGTTACAACAACTATCCTCGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGAGGTCGAGTTGGAAGATCACCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCAATGCTTCGGTGTCGAGAAGAGATAAAGGTTATGAA
TAAAAAAGGAGGGTTTAACAATGAAGTGTCTGCTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TQ48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae D39

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae R6

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae TIGR4

55.684

98.178

0.547
  comFA/cflA Streptococcus mitis NCTC 12261

54.839

98.861

0.542
  comFA/cflA Streptococcus mitis SK321

54.292

98.178

0.533
  comFA Lactococcus lactis subsp. cremoris KW2

45.952

95.672

0.44
  comFA Latilactobacillus sakei subsp. sakei 23K

36.782

99.089

0.364

Multiple sequence alignment