Detailed information NTG1082594

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: ACK2VV_RS07485
• Genome accession: NZ_CP176712
• Coordinates: 1578420..1579106 (-)
• Length: 228 a.a.
• NCBI ID: WP_001802022.1
• Uniprot ID: A0A7U7EYP5
• Organism: Staphylococcus aureus strain GTVSS-008
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1573420..1584106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACK2VV_RS07465 (ACK2VV_07465)	rpsT	1574334..1574585 (+)	252	WP_001274017.1	30S ribosomal protein S20	-
ACK2VV_RS07470 (ACK2VV_07470)	holA	1574630..1575604 (-)	975	WP_001282563.1	DNA polymerase III subunit delta	-
ACK2VV_RS07475 (ACK2VV_07475)	comEC	1575661..1577862 (-)	2202	WP_001557362.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACK2VV_RS07480 (ACK2VV_07480)	-	1577867..1578328 (-)	462	WP_000439693.1	ComE operon protein 2	-
ACK2VV_RS07485 (ACK2VV_07485)	comEA	1578420..1579106 (-)	687	WP_001802022.1	ComEA family DNA-binding protein	Machinery gene
ACK2VV_RS07490 (ACK2VV_07490)	-	1579146..1579862 (-)	717	WP_000084830.1	class I SAM-dependent DNA methyltransferase	-
ACK2VV_RS07495 (ACK2VV_07495)	rsfS	1579865..1580218 (-)	354	WP_001088020.1	ribosome silencing factor	-
ACK2VV_RS07500 (ACK2VV_07500)	yqeK	1580219..1580803 (-)	585	WP_001019324.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ACK2VV_RS07505 (ACK2VV_07505)	nadD	1580793..1581362 (-)	570	WP_000725167.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
ACK2VV_RS07510 (ACK2VV_07510)	yhbY	1581365..1581654 (-)	290	Protein_1473	ribosome assembly RNA-binding protein YhbY	-
ACK2VV_RS07515 (ACK2VV_07515)	aroE	1581658..1582464 (-)	807	WP_000666757.1	shikimate dehydrogenase	-
ACK2VV_RS07520 (ACK2VV_07520)	yqeH	1582478..1583578 (-)	1101	WP_001280137.1	ribosome biogenesis GTPase YqeH	-
ACK2VV_RS07525 (ACK2VV_07525)	-	1583579..1584106 (-)	528	WP_000524903.1	YqeG family HAD IIIA-type phosphatase	-

Sequence

Protein

• Length: 228 a.a.
• Molecular weight: 25900.65 Da
• Isoelectric Point: 9.6751

>NTDB_id=1082594 ACK2VV_RS07485 WP_001802022.1 1578420..1579106(-) (comEA) [Staphylococcus aureus strain GTVSS-008]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide

• Length: 687 bp

>NTDB_id=1082594 ACK2VV_RS07485 WP_001802022.1 1578420..1579106(-) (comEA) [Staphylococcus aureus strain GTVSS-008]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (164-227)

3D structure

• AlphaFold DB: A0A7U7EYP5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Staphylococcus aureus N315	100	100	1
comEA	Staphylococcus aureus MW2	97.368	100	0.974