Detailed information NTG1082579

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACK2VV_RS04465
• Genome accession: NZ_CP176712
• Coordinates: 930264..931250 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain GTVSS-008
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 925264..936250

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACK2VV_RS04440 (ACK2VV_04440)	opp4B	925478..926440 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACK2VV_RS04445 (ACK2VV_04445)	opp4C	926452..927333 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACK2VV_RS04450 (ACK2VV_04450)	trpS	927375..928364 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACK2VV_RS04455 (ACK2VV_04455)	spxA	928658..929053 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACK2VV_RS04460 (ACK2VV_04460)	mecA	929424..930143 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACK2VV_RS04465 (ACK2VV_04465)	coiA	930264..931250 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACK2VV_RS04470 (ACK2VV_04470)	pepF	931298..933106 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACK2VV_RS04475 (ACK2VV_04475)	yjbH	933566..934372 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACK2VV_RS04480 (ACK2VV_04480)	-	934395..934760 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACK2VV_RS04485 (ACK2VV_04485)	-	934864..935457 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACK2VV_RS04490 (ACK2VV_04490)	-	935643..935990 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1082579 ACK2VV_RS04465 WP_000959282.1 930264..931250(+) (coiA) [Staphylococcus aureus strain GTVSS-008]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1082579 ACK2VV_RS04465 WP_000959282.1 930264..931250(+) (coiA) [Staphylococcus aureus strain GTVSS-008]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976