Detailed information NTG0108182

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: FH07_RS01115
• Genome accession: NZ_CP008697
• Coordinates: 220345..221370 (-)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 215345..226370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FH07_RS01085 (FH07_01865)	zapB	215429..215674 (+)	246	WP_001296623.1	septal ring assembly protein ZapB	-
FH07_RS01090 (FH07_01870)	rraA	215759..216244 (-)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
FH07_RS01095 (FH07_01875)	menA	216337..217263 (-)	927	WP_001305044.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
FH07_RS01100 (FH07_01880)	hslU	217330..218661 (-)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
FH07_RS01105 (FH07_01885)	hslV	218671..219201 (-)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
FH07_RS01110 (FH07_01890)	ftsN	219294..220253 (-)	960	WP_000068834.1	cell division protein FtsN	-
FH07_RS01115 (FH07_01895)	cytR	220345..221370 (-)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
FH07_RS01120 (FH07_01900)	priA	221526..223724 (-)	2199	WP_022646377.1	primosomal protein N'	Machinery gene
FH07_RS01125 (FH07_01905)	rpmE	223927..224139 (+)	213	WP_000710769.1	50S ribosomal protein L31	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=108182 FH07_RS01115 WP_000644904.1 220345..221370(-) (cytR) [Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=108182 FH07_RS01115 WP_000644904.1 220345..221370(-) (cytR) [Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGACCCT
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTACCTACCGTTCATATAGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGTGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628