Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACK2I7_RS06160 Genome accession   NZ_CP176632
Coordinates   1252036..1252725 (-) Length   229 a.a.
NCBI ID   WP_057489790.1    Uniprot ID   A0AAP6ENS5
Organism   Streptococcus anginosus strain SFAD 40     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1247036..1257725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS06140 nrdR 1247521..1247994 (-) 474 WP_003023591.1 transcriptional regulator NrdR -
  ACK2I7_RS06145 - 1248160..1248756 (+) 597 WP_021001979.1 hypothetical protein -
  ACK2I7_RS06150 - 1248803..1249618 (-) 816 WP_021001980.1 endonuclease/exonuclease/phosphatase family protein -
  ACK2I7_RS06155 - 1249635..1251824 (-) 2190 WP_084740366.1 PTS transporter subunit IIBC -
  ACK2I7_RS06160 covR 1252036..1252725 (-) 690 WP_057489790.1 DNA-binding response regulator Regulator
  ACK2I7_RS06165 gndA 1252734..1254158 (-) 1425 WP_021001983.1 NADP-dependent phosphogluconate dehydrogenase -
  ACK2I7_RS06170 - 1254457..1255080 (-) 624 WP_003023578.1 DNA alkylation repair protein -
  ACK2I7_RS06175 - 1255131..1255667 (-) 537 WP_021001984.1 DUF177 domain-containing protein -
  ACK2I7_RS06180 - 1255777..1256634 (+) 858 Protein_1203 XRE family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26516.65 Da        Isoelectric Point: 6.2732

>NTDB_id=1081722 ACK2I7_RS06160 WP_057489790.1 1252036..1252725(-) (covR) [Streptococcus anginosus strain SFAD 40]
MAKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKLASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIVGQKSYIKTVRGVGYVMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1081722 ACK2I7_RS06160 WP_057489790.1 1252036..1252725(-) (covR) [Streptococcus anginosus strain SFAD 40]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAATTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCTTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGTGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGTTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.852

100

0.459

Multiple sequence alignment