Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACKZ7U_RS08605 Genome accession   NZ_CP176568
Coordinates   1722170..1722856 (-) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain IMT39173     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1717170..1727856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKZ7U_RS08585 (ACKZ7U_08585) rpsT 1718084..1718335 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  ACKZ7U_RS08590 (ACKZ7U_08590) holA 1718380..1719354 (-) 975 WP_001282568.1 DNA polymerase III subunit delta -
  ACKZ7U_RS08595 (ACKZ7U_08595) comEC 1719411..1721612 (-) 2202 WP_001566670.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACKZ7U_RS08600 (ACKZ7U_08600) - 1721617..1722078 (-) 462 WP_000439693.1 ComE operon protein 2 -
  ACKZ7U_RS08605 (ACKZ7U_08605) comEA 1722170..1722856 (-) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  ACKZ7U_RS08610 (ACKZ7U_08610) - 1722896..1723612 (-) 717 WP_148844403.1 class I SAM-dependent DNA methyltransferase -
  ACKZ7U_RS08615 (ACKZ7U_08615) rsfS 1723615..1723968 (-) 354 WP_001088022.1 ribosome silencing factor -
  ACKZ7U_RS08620 (ACKZ7U_08620) yqeK 1723969..1724553 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACKZ7U_RS08625 (ACKZ7U_08625) nadD 1724543..1725112 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACKZ7U_RS08630 (ACKZ7U_08630) yhbY 1725115..1725405 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  ACKZ7U_RS08635 (ACKZ7U_08635) aroE 1725409..1726215 (-) 807 WP_000666748.1 shikimate dehydrogenase -
  ACKZ7U_RS08640 (ACKZ7U_08640) yqeH 1726229..1727329 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=1080990 ACKZ7U_RS08605 WP_001793467.1 1722170..1722856(-) (comEA) [Staphylococcus aureus strain IMT39173]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1080990 ACKZ7U_RS08605 WP_001793467.1 1722170..1722856(-) (comEA) [Staphylococcus aureus strain IMT39173]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974

Multiple sequence alignment