Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACKZ7U_RS02925 Genome accession   NZ_CP176568
Coordinates   585234..585803 (+) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain IMT39173     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 580234..590803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKZ7U_RS02900 (ACKZ7U_02900) cysE 581447..582094 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  ACKZ7U_RS02905 (ACKZ7U_02905) cysS 582078..583478 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  ACKZ7U_RS02910 (ACKZ7U_02910) - 583471..583875 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  ACKZ7U_RS02915 (ACKZ7U_02915) rlmB 583883..584629 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACKZ7U_RS02920 (ACKZ7U_02920) - 584629..585153 (+) 525 WP_000664738.1 NYN domain-containing protein -
  ACKZ7U_RS02925 (ACKZ7U_02925) sigH 585234..585803 (+) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACKZ7U_RS02930 (ACKZ7U_02930) rpmG 585918..586061 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACKZ7U_RS02935 (ACKZ7U_02935) secE 586117..586299 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACKZ7U_RS02940 (ACKZ7U_02940) nusG 586312..586860 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACKZ7U_RS02945 (ACKZ7U_02945) rplK 587041..587463 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACKZ7U_RS02950 (ACKZ7U_02950) rplA 587671..588363 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACKZ7U_RS02955 (ACKZ7U_02955) rplJ 588635..589135 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  ACKZ7U_RS02960 (ACKZ7U_02960) rplL 589178..589546 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACKZ7U_RS02965 (ACKZ7U_02965) - 589721..590329 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=1080970 ACKZ7U_RS02925 WP_000872877.1 585234..585803(+) (sigH) [Staphylococcus aureus strain IMT39173]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1080970 ACKZ7U_RS02925 WP_000872877.1 585234..585803(+) (sigH) [Staphylococcus aureus strain IMT39173]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment