Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACKWPP_RS06215 Genome accession   NZ_CP176418
Coordinates   1186945..1188171 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain KKAHC02     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1181945..1193171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWPP_RS06185 (ACKWPP_06185) - 1181973..1182197 (-) 225 WP_002934981.1 hypothetical protein -
  ACKWPP_RS06190 (ACKWPP_06190) - 1182259..1183572 (-) 1314 WP_141587744.1 excalibur calcium-binding domain-containing protein -
  ACKWPP_RS06195 (ACKWPP_06195) - 1183707..1183889 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  ACKWPP_RS06200 (ACKWPP_06200) lepA 1183939..1185771 (-) 1833 WP_002943192.1 translation elongation factor 4 -
  ACKWPP_RS06205 (ACKWPP_06205) ndk 1185851..1186279 (-) 429 WP_044755163.1 nucleoside-diphosphate kinase -
  ACKWPP_RS06210 (ACKWPP_06210) yihA 1186302..1186889 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACKWPP_RS06215 (ACKWPP_06215) clpX 1186945..1188171 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACKWPP_RS06220 (ACKWPP_06220) - 1188369..1188881 (-) 513 WP_141587743.1 dihydrofolate reductase -
  ACKWPP_RS06225 (ACKWPP_06225) - 1189218..1190057 (-) 840 WP_409373661.1 thymidylate synthase -
  ACKWPP_RS06230 (ACKWPP_06230) - 1190110..1190412 (-) 303 WP_012775088.1 hypothetical protein -
  ACKWPP_RS06235 (ACKWPP_06235) - 1190424..1190702 (-) 279 WP_024381822.1 hypothetical protein -
  ACKWPP_RS06240 (ACKWPP_06240) - 1190829..1191788 (-) 960 WP_409373662.1 ROK family glucokinase -
  ACKWPP_RS06245 (ACKWPP_06245) - 1191884..1192219 (-) 336 WP_409373663.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=1080064 ACKWPP_RS06215 WP_002934974.1 1186945..1188171(-) (clpX) [Streptococcus suis strain KKAHC02]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1080064 ACKWPP_RS06215 WP_002934974.1 1186945..1188171(-) (clpX) [Streptococcus suis strain KKAHC02]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
TGGGAACAATGTCTTCATTTGTAATGAATGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTATGTCATCGGACAGGATCGTGCT
AAGCGTGCCTTGGCAGTTGCTGTCTACAACCACTACAAACGGATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTACAAAAATCAAATATCCTTATGATTGGTCCGACTGGTTCAGGAAAAACCTTCCTAGCACAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTGGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAA
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment