Detailed information NTG1080058

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACKWPP_RS03125
• Genome accession: NZ_CP176418
• Coordinates: 561523..563751 (-)
• Length: 742 a.a.
• NCBI ID: WP_409374164.1
• Uniprot ID: -
• Organism: Streptococcus suis strain KKAHC02
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 556523..568751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKWPP_RS03105 (ACKWPP_03105)	-	556892..557335 (+)	444	WP_044674773.1	GNAT family N-acetyltransferase	-
ACKWPP_RS03110 (ACKWPP_03110)	ileS	557346..560135 (+)	2790	WP_141587887.1	isoleucine--tRNA ligase	-
ACKWPP_RS03115 (ACKWPP_03115)	-	560512..560820 (-)	309	WP_002938710.1	DUF1827 family protein	-
ACKWPP_RS03120 (ACKWPP_03120)	-	560875..561336 (-)	462	WP_002938708.1	NUDIX hydrolase	-
ACKWPP_RS03125 (ACKWPP_03125)	clpE	561523..563751 (-)	2229	WP_409374164.1	AAA family ATPase	Regulator
ACKWPP_RS03130 (ACKWPP_03130)	-	563975..564205 (+)	231	WP_002938704.1	DUF1797 family protein	-
ACKWPP_RS03135 (ACKWPP_03135)	-	564331..565020 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
ACKWPP_RS03140 (ACKWPP_03140)	-	565013..565747 (+)	735	WP_002943067.1	amino acid ABC transporter ATP-binding protein	-
ACKWPP_RS03145 (ACKWPP_03145)	-	565877..566725 (+)	849	WP_409374165.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82639.04 Da
• Isoelectric Point: 5.2782

>NTDB_id=1080058 ACKWPP_RS03125 WP_409374164.1 561523..563751(-) (clpE) [Streptococcus suis strain KKAHC02]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKVHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDIMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=1080058 ACKWPP_RS03125 WP_409374164.1 561523..563751(-) (clpE) [Streptococcus suis strain KKAHC02]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAACAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTCTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTTGACGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTCCCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGTCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATATCATGCACATGTTCCTTCAGGTCTTAGACGATGGTCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACCATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CCATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (291-389)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.228	100	0.836
clpE	Streptococcus pneumoniae D39	82.228	100	0.836
clpE	Streptococcus pneumoniae R6	82.228	100	0.836
clpE	Streptococcus pneumoniae TIGR4	82.228	100	0.836
clpE	Streptococcus mutans UA159	82.243	100	0.83
clpC	Lactococcus lactis subsp. cremoris KW2	77.379	97.709	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	52.308	87.601	0.458
clpC	Streptococcus thermophilus LMD-9	48.408	84.636	0.41
clpC	Streptococcus mutans UA159	48.718	84.097	0.41
clpC	Streptococcus thermophilus LMG 18311	48.089	84.636	0.407
clpC	Streptococcus pneumoniae Rx1	48	84.232	0.404
clpC	Streptococcus pneumoniae D39	48	84.232	0.404
clpC	Streptococcus pneumoniae TIGR4	48	84.232	0.404
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.656	84.636	0.395