Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   AACH35_RS13435 Genome accession   NZ_AP028993
Coordinates   2691865..2692530 (-) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain TUM19959     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2686865..2697530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACH35_RS13415 - 2687330..2687443 (-) 114 WP_072384844.1 hypothetical protein -
  AACH35_RS13420 (TUM19959_25260) - 2688107..2690107 (-) 2001 WP_000776746.1 ABC transporter permease -
  AACH35_RS13425 (TUM19959_25270) - 2690104..2690859 (-) 756 WP_000923768.1 ABC transporter ATP-binding protein -
  AACH35_RS13430 (TUM19959_25280) braS 2690967..2691854 (-) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  AACH35_RS13435 (TUM19959_25290) braR 2691865..2692530 (-) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  AACH35_RS13440 (TUM19959_25300) - 2692556..2692756 (-) 201 WP_000604723.1 hypothetical protein -
  AACH35_RS13445 (TUM19959_25310) - 2692954..2694303 (+) 1350 WP_000953732.1 alkaline phosphatase -
  AACH35_RS13450 - 2694373..2694483 (+) 111 WP_001791296.1 hypothetical protein -
  AACH35_RS13455 (TUM19959_25320) - 2694586..2695041 (-) 456 WP_000106184.1 MarR family transcriptional regulator -
  AACH35_RS13460 (TUM19959_25330) - 2695287..2696048 (-) 762 WP_000323451.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=107913 AACH35_RS13435 WP_000697883.1 2691865..2692530(-) (braR) [Staphylococcus aureus strain TUM19959]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=107913 AACH35_RS13435 WP_000697883.1 2691865..2692530(-) (braR) [Staphylococcus aureus strain TUM19959]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACGGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGACAATACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATTATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment