Detailed information NTG0107912

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AACH35_RS13430
• Genome accession: NZ_AP028993
• Coordinates: 2690967..2691854 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain TUM19959
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2685967..2696854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AACH35_RS13400	-	2685985..2686073 (+)	89	Protein_2605	hypothetical protein	-
AACH35_RS13405 (TUM19959_25240)	-	2686181..2686678 (-)	498	WP_101244946.1	glutathione peroxidase	-
AACH35_RS13410 (TUM19959_25250)	-	2686688..2686948 (-)	261	WP_072434822.1	hypothetical protein	-
AACH35_RS13415	-	2687330..2687443 (-)	114	WP_072384844.1	hypothetical protein	-
AACH35_RS13420 (TUM19959_25260)	-	2688107..2690107 (-)	2001	WP_000776746.1	ABC transporter permease	-
AACH35_RS13425 (TUM19959_25270)	-	2690104..2690859 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
AACH35_RS13430 (TUM19959_25280)	braS	2690967..2691854 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AACH35_RS13435 (TUM19959_25290)	braR	2691865..2692530 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AACH35_RS13440 (TUM19959_25300)	-	2692556..2692756 (-)	201	WP_000604723.1	hypothetical protein	-
AACH35_RS13445 (TUM19959_25310)	-	2692954..2694303 (+)	1350	WP_000953732.1	alkaline phosphatase	-
AACH35_RS13450	-	2694373..2694483 (+)	111	WP_001791296.1	hypothetical protein	-
AACH35_RS13455 (TUM19959_25320)	-	2694586..2695041 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
AACH35_RS13460 (TUM19959_25330)	-	2695287..2696048 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=107912 AACH35_RS13430 WP_000143420.1 2690967..2691854(-) (braS) [Staphylococcus aureus strain TUM19959]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=107912 AACH35_RS13430 WP_000143420.1 2690967..2691854(-) (braS) [Staphylococcus aureus strain TUM19959]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993