Detailed information NTG0107827

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AACH49_RS13760
• Genome accession: NZ_AP028991
• Coordinates: 2749976..2750863 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain TUM19381
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2744976..2755863

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AACH49_RS13730	-	2744994..2745082 (+)	89	Protein_2663	hypothetical protein	-
AACH49_RS13735 (TUM19381_25840)	-	2745190..2745687 (-)	498	WP_101244946.1	glutathione peroxidase	-
AACH49_RS13740 (TUM19381_25850)	-	2745697..2745957 (-)	261	WP_072434822.1	hypothetical protein	-
AACH49_RS13745	-	2746339..2746452 (-)	114	WP_072384844.1	hypothetical protein	-
AACH49_RS13750 (TUM19381_25860)	-	2747116..2749116 (-)	2001	WP_000776746.1	ABC transporter permease	-
AACH49_RS13755 (TUM19381_25870)	-	2749113..2749868 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
AACH49_RS13760 (TUM19381_25880)	braS	2749976..2750863 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AACH49_RS13765 (TUM19381_25890)	braR	2750874..2751539 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AACH49_RS13770 (TUM19381_25900)	-	2751565..2751765 (-)	201	WP_000604723.1	hypothetical protein	-
AACH49_RS13775 (TUM19381_25910)	-	2751963..2753312 (+)	1350	WP_000953732.1	alkaline phosphatase	-
AACH49_RS13780	-	2753382..2753492 (+)	111	WP_001791296.1	hypothetical protein	-
AACH49_RS13785 (TUM19381_25920)	-	2753595..2754050 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
AACH49_RS13790 (TUM19381_25930)	-	2754296..2755057 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=107827 AACH49_RS13760 WP_000143420.1 2749976..2750863(-) (braS) [Staphylococcus aureus strain TUM19381]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=107827 AACH49_RS13760 WP_000143420.1 2749976..2750863(-) (braS) [Staphylococcus aureus strain TUM19381]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993