Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   AACH49_RS06525 Genome accession   NZ_AP028991
Coordinates   1312953..1314023 (+) Length   356 a.a.
NCBI ID   WP_000776403.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM19381     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1307953..1319023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACH49_RS06495 (TUM19381_12010) - 1308376..1309839 (+) 1464 WP_001017872.1 rhomboid family intramembrane serine protease -
  AACH49_RS06500 (TUM19381_12020) - 1309820..1310023 (+) 204 WP_000087561.1 YqgQ family protein -
  AACH49_RS06505 (TUM19381_12030) - 1310020..1311006 (+) 987 WP_000161315.1 ROK family glucokinase -
  AACH49_RS06510 (TUM19381_12040) - 1311006..1311335 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  AACH49_RS06515 (TUM19381_12050) - 1311332..1311955 (+) 624 WP_001223006.1 MBL fold metallo-hydrolase -
  AACH49_RS06520 (TUM19381_12060) comGA 1312007..1312981 (+) 975 WP_000697215.1 competence type IV pilus ATPase ComGA Machinery gene
  AACH49_RS06525 (TUM19381_12070) comGB 1312953..1314023 (+) 1071 WP_000776403.1 competence type IV pilus assembly protein ComGB Machinery gene
  AACH49_RS06530 (TUM19381_12080) comGC 1314037..1314348 (+) 312 WP_101262880.1 competence type IV pilus major pilin ComGC Machinery gene
  AACH49_RS06535 (TUM19381_12090) comGD 1314326..1314772 (+) 447 WP_075583651.1 competence type IV pilus minor pilin ComGD Machinery gene
  AACH49_RS06540 (TUM19381_12100) comGE 1314759..1315058 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  AACH49_RS06545 (TUM19381_12110) comGF 1314976..1315473 (+) 498 WP_029697681.1 competence type IV pilus minor pilin ComGF Machinery gene
  AACH49_RS06550 - 1315570..1315716 (+) 147 WP_001789879.1 hypothetical protein -
  AACH49_RS06555 (TUM19381_12120) - 1315706..1316230 (+) 525 WP_001015122.1 shikimate kinase -
  AACH49_RS06560 (TUM19381_12130) gcvT 1316389..1317480 (+) 1092 WP_000093355.1 glycine cleavage system aminomethyltransferase GcvT -
  AACH49_RS06565 (TUM19381_12140) gcvPA 1317500..1318846 (+) 1347 WP_000019688.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41487.99 Da        Isoelectric Point: 10.1030

>NTDB_id=107809 AACH49_RS06525 WP_000776403.1 1312953..1314023(+) (comGB) [Staphylococcus aureus strain TUM19381]
MKLQWINTFKLHSKKRQLSKAQQIDLLLNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNKLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=107809 AACH49_RS06525 WP_000776403.1 1312953..1314023(+) (comGB) [Staphylococcus aureus strain TUM19381]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTTAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGCACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAACCAGATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATCATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCGATTTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAAATTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CGGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTATTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTACCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGAAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTGGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.438

100

0.994
  comGB Staphylococcus aureus N315

99.438

100

0.994

Multiple sequence alignment