Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACJEH8_RS13500 Genome accession   NZ_CP174244
Coordinates   3037123..3037782 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila strain SPF580     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3032123..3042782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJEH8_RS13485 (ACJEH8_13485) - 3033076..3033735 (+) 660 WP_011216515.1 hypothetical protein -
  ACJEH8_RS13490 (ACJEH8_13490) lcl 3033903..3035231 (+) 1329 WP_070322485.1 collagen-like adhesin Lcl -
  ACJEH8_RS13495 (ACJEH8_13495) uvrC 3035255..3037111 (-) 1857 WP_011216517.1 excinuclease ABC subunit UvrC -
  ACJEH8_RS13500 (ACJEH8_13500) letA 3037123..3037782 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  ACJEH8_RS13505 (ACJEH8_13505) phhA 3037907..3038725 (-) 819 WP_027266285.1 phenylalanine 4-monooxygenase -
  ACJEH8_RS13510 (ACJEH8_13510) - 3039166..3040263 (+) 1098 WP_011216520.1 molybdopterin-binding protein -
  ACJEH8_RS13515 (ACJEH8_13515) cgtA 3040222..3041247 (-) 1026 WP_011216521.1 Obg family GTPase CgtA -
  ACJEH8_RS13520 (ACJEH8_13520) rpmA 3041461..3041739 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  ACJEH8_RS13525 (ACJEH8_13525) rplU 3041752..3042063 (-) 312 WP_011216522.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=1076488 ACJEH8_RS13500 WP_011216518.1 3037123..3037782(-) (letA) [Legionella pneumophila strain SPF580]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1076488 ACJEH8_RS13500 WP_011216518.1 3037123..3037782(-) (letA) [Legionella pneumophila strain SPF580]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTGGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTGGCCTATGTGAAAACCCACTCCCCTGATGTCGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACACGTCGCTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCA
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCCGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCCAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTCCAGGAGTCTCAGGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment