Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACJEH2_RS05445 Genome accession   NZ_CP174235
Coordinates   1262148..1262807 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila strain SPF590     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1257148..1267807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJEH2_RS05430 (ACJEH2_05430) - 1258101..1258760 (+) 660 WP_011216515.1 hypothetical protein -
  ACJEH2_RS05435 (ACJEH2_05435) lcl 1258928..1260256 (+) 1329 WP_070322485.1 collagen-like adhesin Lcl -
  ACJEH2_RS05440 (ACJEH2_05440) uvrC 1260280..1262136 (-) 1857 WP_011216517.1 excinuclease ABC subunit UvrC -
  ACJEH2_RS05445 (ACJEH2_05445) letA 1262148..1262807 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  ACJEH2_RS05450 (ACJEH2_05450) phhA 1262932..1263750 (-) 819 WP_027266285.1 phenylalanine 4-monooxygenase -
  ACJEH2_RS05455 (ACJEH2_05455) - 1264191..1265288 (+) 1098 WP_011216520.1 molybdopterin-binding protein -
  ACJEH2_RS05460 (ACJEH2_05460) cgtA 1265247..1266272 (-) 1026 WP_011216521.1 Obg family GTPase CgtA -
  ACJEH2_RS05465 (ACJEH2_05465) rpmA 1266486..1266764 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  ACJEH2_RS05470 (ACJEH2_05470) rplU 1266777..1267088 (-) 312 WP_011216522.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=1076090 ACJEH2_RS05445 WP_011216518.1 1262148..1262807(-) (letA) [Legionella pneumophila strain SPF590]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1076090 ACJEH2_RS05445 WP_011216518.1 1262148..1262807(-) (letA) [Legionella pneumophila strain SPF590]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTGGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTGGCCTATGTGAAAACCCACTCCCCTGATGTCGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACACGTCGCTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCA
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCCGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCCAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTCCAGGAGTCTCAGGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment