Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACJEHF_RS12230 Genome accession   NZ_CP174233
Coordinates   2707358..2708017 (+) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila strain SPF601     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2702358..2713017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJEHF_RS12205 (ACJEHF_12205) rplU 2703078..2703389 (+) 312 WP_010948351.1 50S ribosomal protein L21 -
  ACJEHF_RS12210 (ACJEHF_12210) rpmA 2703402..2703680 (+) 279 WP_010948350.1 50S ribosomal protein L27 -
  ACJEHF_RS12215 (ACJEHF_12215) cgtA 2703895..2704920 (+) 1026 WP_010948349.1 Obg family GTPase CgtA -
  ACJEHF_RS12220 (ACJEHF_12220) - 2704879..2705976 (-) 1098 WP_010948348.1 molybdopterin-binding protein -
  ACJEHF_RS12225 (ACJEHF_12225) phhA 2706415..2707233 (+) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  ACJEHF_RS12230 (ACJEHF_12230) letA 2707358..2708017 (+) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  ACJEHF_RS12235 (ACJEHF_12235) uvrC 2708029..2709885 (+) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  ACJEHF_RS12240 (ACJEHF_12240) lcl 2709909..2711390 (-) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  ACJEHF_RS12245 (ACJEHF_12245) - 2711558..2712217 (-) 660 WP_010948343.1 hypothetical protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=1076026 ACJEHF_RS12230 WP_011216518.1 2707358..2708017(+) (letA) [Legionella pneumophila strain SPF601]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1076026 ACJEHF_RS12230 WP_011216518.1 2707358..2708017(+) (letA) [Legionella pneumophila strain SPF601]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment