Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACJEH7_RS12580 Genome accession   NZ_CP174227
Coordinates   2841729..2842388 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila strain SPF639     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2836729..2847388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJEH7_RS12565 (ACJEH7_12565) - 2837529..2838188 (+) 660 WP_010948343.1 hypothetical protein -
  ACJEH7_RS12570 (ACJEH7_12570) lcl 2838356..2839837 (+) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  ACJEH7_RS12575 (ACJEH7_12575) uvrC 2839861..2841717 (-) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  ACJEH7_RS12580 (ACJEH7_12580) letA 2841729..2842388 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  ACJEH7_RS12585 (ACJEH7_12585) phhA 2842513..2843331 (-) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  ACJEH7_RS12590 (ACJEH7_12590) - 2843770..2844867 (+) 1098 WP_010948348.1 molybdopterin-binding protein -
  ACJEH7_RS12595 (ACJEH7_12595) cgtA 2844826..2845851 (-) 1026 WP_010948349.1 Obg family GTPase CgtA -
  ACJEH7_RS12600 (ACJEH7_12600) rpmA 2846066..2846344 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  ACJEH7_RS12605 (ACJEH7_12605) rplU 2846357..2846668 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=1075774 ACJEH7_RS12580 WP_011216518.1 2841729..2842388(-) (letA) [Legionella pneumophila strain SPF639]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1075774 ACJEH7_RS12580 WP_011216518.1 2841729..2842388(-) (letA) [Legionella pneumophila strain SPF639]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment