Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACJEIG_RS12225 Genome accession   NZ_CP174209
Coordinates   2706278..2706937 (+) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila strain SPF666     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2701278..2711937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJEIG_RS12200 (ACJEIG_12200) rplU 2701998..2702309 (+) 312 WP_010948351.1 50S ribosomal protein L21 -
  ACJEIG_RS12205 (ACJEIG_12205) rpmA 2702322..2702600 (+) 279 WP_010948350.1 50S ribosomal protein L27 -
  ACJEIG_RS12210 (ACJEIG_12210) cgtA 2702815..2703840 (+) 1026 WP_010948349.1 Obg family GTPase CgtA -
  ACJEIG_RS12215 (ACJEIG_12215) - 2703799..2704896 (-) 1098 WP_010948348.1 molybdopterin-binding protein -
  ACJEIG_RS12220 (ACJEIG_12220) phhA 2705335..2706153 (+) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  ACJEIG_RS12225 (ACJEIG_12225) letA 2706278..2706937 (+) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  ACJEIG_RS12230 (ACJEIG_12230) uvrC 2706949..2708805 (+) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  ACJEIG_RS12235 (ACJEIG_12235) lcl 2708829..2710310 (-) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  ACJEIG_RS12240 (ACJEIG_12240) - 2710478..2711137 (-) 660 WP_010948343.1 hypothetical protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=1075020 ACJEIG_RS12225 WP_011216518.1 2706278..2706937(+) (letA) [Legionella pneumophila strain SPF666]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1075020 ACJEIG_RS12225 WP_011216518.1 2706278..2706937(+) (letA) [Legionella pneumophila strain SPF666]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment