Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   ACAM22_RS08245 Genome accession   NZ_AP028929
Coordinates   1797400..1798224 (-) Length   274 a.a.
NCBI ID   WP_153226562.1    Uniprot ID   -
Organism   Streptococcus sp. SN-1     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1792400..1803224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS08230 (MASAN616_15990) amiA3 1793497..1795485 (-) 1989 WP_369606672.1 peptide ABC transporter substrate-binding protein Regulator
  ACAM22_RS08240 (MASAN616_16000) - 1795914..1797245 (-) 1332 WP_369606673.1 hemolysin family protein -
  ACAM22_RS08245 (MASAN616_16010) endA 1797400..1798224 (-) 825 WP_153226562.1 DNA-entry nuclease EndA Machinery gene
  ACAM22_RS08250 (MASAN616_16020) - 1798263..1798451 (-) 189 WP_025171934.1 DNA-directed RNA polymerase subunit beta -
  ACAM22_RS08255 (MASAN616_16030) murA 1798444..1799727 (-) 1284 WP_000411904.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ACAM22_RS08260 - 1799739..1800781 (-) 1043 Protein_1614 acyltransferase family protein -
  ACAM22_RS08265 (MASAN616_16060) - 1800843..1801073 (-) 231 WP_063612229.1 DUF1146 family protein -
  ACAM22_RS08270 (MASAN616_16070) sepM 1801131..1802168 (-) 1038 WP_000727281.1 SepM family pheromone-processing serine protease Regulator
  ACAM22_RS08275 (MASAN616_16080) coaD 1802152..1802640 (-) 489 WP_261052399.1 pantetheine-phosphate adenylyltransferase -
  ACAM22_RS08280 (MASAN616_16090) rsmD 1802630..1803169 (-) 540 WP_004248990.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29937.56 Da        Isoelectric Point: 9.8711

>NTDB_id=107350 ACAM22_RS08245 WP_153226562.1 1797400..1798224(-) (endA) [Streptococcus sp. SN-1]
MNKKTRQTLIGLLVLLLLSAGSYYIKQMQSTANSPKTKLSQKKQASEAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESMVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=107350 ACAM22_RS08245 WP_153226562.1 1797400..1798224(-) (endA) [Streptococcus sp. SN-1]
ATGAATAAAAAAACAAGACAGACACTGATCGGACTGCTAGTGTTATTACTCTTATCTGCGGGAAGCTACTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCCAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGAATTGG
CAGAAAGTGTCTTAACAGATGCAGTCAAAAGCCAAATAAAAGGGAGCCTGGAGTGGAATGGATCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGATAATAAAACAAAGACAGTGGGCAAGGA
AACGGTACCAACCGTAGCTAATGCACTCTTGTCTAAGGCTACTCGCCAGTACAAGAATCGGGAAGAAACTGGGAATGGTT
CGACTTCTTGGACTCCACCAGGTTGGCATCAGGTCAAGAATCTAAAGGGTACTTATACCCATGCGGTTGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATTGGTGGCTTGGATGGTTTTGATGCCTCAACAAGTAATCCTAAAAATATTGCTGTCCAGAC
AGCCTGGGCCAATCAGGCACAGGCCGAGGATTCGACTGGTCAAAACTACTATGAAAGCATGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTTCGTTACCGTGTAACCCTTTACTACGCTTCGAACGAGGATTTAGTTCCTTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGACGGAGAATTGGAATTTAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

96.35

100

0.964
  endA Streptococcus pneumoniae D39

96.35

100

0.964
  endA Streptococcus pneumoniae R6

96.35

100

0.964
  endA Streptococcus pneumoniae TIGR4

96.35

100

0.964

Multiple sequence alignment