Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACAM22_RS01750 Genome accession   NZ_AP028929
Coordinates   378564..379253 (+) Length   229 a.a.
NCBI ID   WP_261030145.1    Uniprot ID   A0AAT9FYY9
Organism   Streptococcus sp. SN-1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 373564..384253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS01725 (MASAN616_03380) gpsB 373663..373992 (+) 330 WP_023945225.1 cell division regulator GpsB -
  ACAM22_RS01735 (MASAN616_03390) - 374478..375635 (+) 1158 WP_369606844.1 class I SAM-dependent RNA methyltransferase -
  ACAM22_RS01740 (MASAN616_03400) - 375649..377052 (+) 1404 WP_261051176.1 cell division site-positioning protein MapZ family protein -
  ACAM22_RS01745 (MASAN616_03410) gndA 377128..378552 (+) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  ACAM22_RS01750 (MASAN616_03420) covR 378564..379253 (+) 690 WP_261030145.1 response regulator transcription factor Regulator
  ACAM22_RS01755 (MASAN616_03430) - 379353..380294 (+) 942 WP_369606845.1 N-acetylmuramoyl-L-alanine amidase family protein -
  ACAM22_RS01760 (MASAN616_03440) mvk 380417..381295 (+) 879 WP_261051198.1 mevalonate kinase -
  ACAM22_RS01765 (MASAN616_03450) mvaD 381277..382230 (+) 954 WP_261051201.1 diphosphomevalonate decarboxylase -
  ACAM22_RS01770 (MASAN616_03460) - 382217..383224 (+) 1008 WP_261051203.1 phosphomevalonate kinase -
  ACAM22_RS01775 (MASAN616_03470) fni 383208..384218 (+) 1011 WP_369606846.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26750.80 Da        Isoelectric Point: 7.4648

>NTDB_id=107315 ACAM22_RS01750 WP_261030145.1 378564..379253(+) (covR) [Streptococcus sp. SN-1]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSTALQTDYDLILLNARLGDMTAQDFAEKLSRTKPASVIMVL
DHREELQDQIETIQHFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=107315 ACAM22_RS01750 WP_261030145.1 378564..379253(+) (covR) [Streptococcus sp. SN-1]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCACGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCGTCTGGGGGATATGACAGCCCAGGATTTTGCAGAGAAGCTGAGTAGGACTAAGCCTGCCTCAGTCATTATGGTCTTG
GACCATCGCGAAGAATTGCAAGATCAGATTGAAACAATCCAACACTTTGCCGTTTCTTACATCTATAAGCCGGTTATTAT
TGACAATTTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGATCAACACTGCAGTCAGATGAAGGTTC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAAGAGATGATTGCTCTGACCCGT
CGCGAGTATGACCTCTTGGCTACTCTGATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACAAATATCGTGGATGTCTACATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACAGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment