Detailed information NTG1072112

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ACI2O8_RS13265
• Genome accession: NZ_CP173415
• Coordinates: 2549739..2552069 (-)
• Length: 776 a.a.
• NCBI ID: WP_074794436.1
• Uniprot ID: A0A8E0SBN0
• Organism: Bacillus subtilis strain FJYA24
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2544739..2557069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI2O8_RS13230 (ACI2O8_13230)	yqxA	2545078..2545416 (-)	339	WP_014477382.1	YqxA family protein	-
ACI2O8_RS13235 (ACI2O8_13235)	spoIIP	2545433..2546638 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
ACI2O8_RS13240 (ACI2O8_13240)	gpr	2546701..2547807 (-)	1107	WP_109962781.1	GPR endopeptidase	-
ACI2O8_RS13245 (ACI2O8_13245)	rpsT	2548011..2548277 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
ACI2O8_RS13250 (ACI2O8_13250)	holA	2548292..2549335 (-)	1044	WP_015714286.1	DNA polymerase III subunit delta	-
ACI2O8_RS13255 (ACI2O8_13255)	-	2549375..2549524 (-)	150	WP_003229985.1	hypothetical protein	-
ACI2O8_RS13260 (ACI2O8_13260)	yqzM	2549565..2549699 (+)	135	WP_003229983.1	YqzM family protein	-
ACI2O8_RS13265 (ACI2O8_13265)	comEC	2549739..2552069 (-)	2331	WP_074794436.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACI2O8_RS13270 (ACI2O8_13270)	comEB	2552066..2552635 (-)	570	WP_015714288.1	ComE operon protein 2	-
ACI2O8_RS13275 (ACI2O8_13275)	comEA	2552702..2553319 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
ACI2O8_RS13280 (ACI2O8_13280)	comER	2553403..2554224 (+)	822	WP_004398597.1	late competence protein ComER	-
ACI2O8_RS13285 (ACI2O8_13285)	yqeM	2554290..2555033 (-)	744	WP_003229973.1	class I SAM-dependent methyltransferase	-
ACI2O8_RS13290 (ACI2O8_13290)	rsfS	2555030..2555386 (-)	357	WP_003229971.1	ribosome silencing factor	-
ACI2O8_RS13295 (ACI2O8_13295)	yqeK	2555404..2555964 (-)	561	WP_004399059.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ACI2O8_RS13300 (ACI2O8_13300)	nadD	2555954..2556523 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
ACI2O8_RS13305 (ACI2O8_13305)	yhbY	2556535..2556825 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86642.27 Da
• Isoelectric Point: 7.2477

>NTDB_id=1072112 ACI2O8_RS13265 WP_074794436.1 2549739..2552069(-) (comEC) [Bacillus subtilis strain FJYA24]
MMNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMVVKTPDKEKWAAAYRILSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHTISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVAIILLLMAIEKRSLSQLMITGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
TPDPASKNNSSLVLWMETGVLSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=1072112 ACI2O8_RS13265 WP_074794436.1 2549739..2552069(-) (comEC) [Bacillus subtilis strain FJYA24]
GTGATGAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGGTGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCTGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGAGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATTCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATACCATATCATTCACAAACAGCCTTTTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGACGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTTTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGACAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTTGCGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGATAACCGGCGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
ACACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGTTCTGAGCTGGATTTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	97.809	100	0.978