Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACI2O8_RS06590 Genome accession   NZ_CP173415
Coordinates   1255869..1256525 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis strain FJYA24     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1250869..1261525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI2O8_RS06560 (ACI2O8_06560) oppF 1251334..1252251 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACI2O8_RS06565 (ACI2O8_06565) yjbB 1252358..1253575 (+) 1218 WP_080348083.1 MFS transporter -
  ACI2O8_RS06570 (ACI2O8_06570) yjbC 1253739..1254317 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ACI2O8_RS06575 (ACI2O8_06575) spx 1254498..1254893 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ACI2O8_RS06580 (ACI2O8_06580) yjbE 1254936..1255592 (-) 657 WP_003232944.1 TerC family protein -
  ACI2O8_RS06585 (ACI2O8_06585) - 1255762..1255902 (+) 141 WP_119122854.1 hypothetical protein -
  ACI2O8_RS06590 (ACI2O8_06590) mecA 1255869..1256525 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  ACI2O8_RS06595 (ACI2O8_06595) - 1256520..1256642 (-) 123 WP_122060507.1 hypothetical protein -
  ACI2O8_RS06600 (ACI2O8_06600) coiA 1256686..1257837 (+) 1152 WP_088467623.1 competence protein CoiA Machinery gene
  ACI2O8_RS06605 (ACI2O8_06605) pepF 1258067..1259896 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  ACI2O8_RS06610 (ACI2O8_06610) - 1259934..1260101 (-) 168 WP_003244944.1 hypothetical protein -
  ACI2O8_RS06615 (ACI2O8_06615) spxH 1260416..1261315 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=1072087 ACI2O8_RS06590 WP_003232942.1 1255869..1256525(+) (mecA) [Bacillus subtilis strain FJYA24]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1072087 ACI2O8_RS06590 WP_003232942.1 1255869..1256525(+) (mecA) [Bacillus subtilis strain FJYA24]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment