Detailed information NTG0107208

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: AAA995_RS08880
• Genome accession: NZ_AP028877
• Coordinates: 1739546..1740613 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain 21P20
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1734546..1745613

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA995_RS08855 (SP21P20_17620)	treR	1734733..1735443 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
AAA995_RS08860 (SP21P20_17630)	-	1735476..1736279 (-)	804	WP_000157672.1	ATP-binding cassette domain-containing protein	-
AAA995_RS08865	-	1736292..1737169 (-)	878	Protein_1755	ABC transporter permease	-
AAA995_RS08870	-	1737181..1738118 (-)	938	Protein_1756	ABC transporter substrate-binding protein	-
AAA995_RS08875 (SP21P20_17680)	amiF	1738609..1739535 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
AAA995_RS08880 (SP21P20_17690)	amiE	1739546..1740613 (-)	1068	WP_000159554.1	oligopeptide/dipeptide ABC transporter ATP-binding protein	Regulator
AAA995_RS08885 (SP21P20_17700)	amiD	1740622..1741548 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
AAA995_RS08890 (SP21P20_17710)	amiC	1741548..1743044 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
AAA995_RS08895 (SP21P20_17720)	amiA3	1743111..1745090 (-)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=107208 AAA995_RS08880 WP_000159554.1 1739546..1740613(-) (amiE) [Streptococcus pneumoniae strain 21P20]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=107208 AAA995_RS08880 WP_000159554.1 1739546..1740613(-) (amiE) [Streptococcus pneumoniae strain 21P20]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541