Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   AAA995_RS07475 Genome accession   NZ_AP028877
Coordinates   1469902..1471134 (-) Length   410 a.a.
NCBI ID   WP_000106349.1    Uniprot ID   A0AA95D8Q6
Organism   Streptococcus pneumoniae strain 21P20     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1464902..1476134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA995_RS07445 (SP21P20_14870) - 1465089..1466057 (+) 969 WP_000081003.1 NAD(P)/FAD-dependent oxidoreductase -
  AAA995_RS07450 (SP21P20_14880) whiA 1466091..1467002 (-) 912 WP_000011306.1 DNA-binding protein WhiA -
  AAA995_RS07455 (SP21P20_14890) - 1466999..1467976 (-) 978 WP_001231086.1 YvcK family protein -
  AAA995_RS07460 (SP21P20_14900) rapZ 1467973..1468863 (-) 891 WP_000163035.1 RNase adapter RapZ -
  AAA995_RS07465 (SP21P20_14910) - 1468915..1469295 (-) 381 WP_001140412.1 RidA family protein -
  AAA995_RS07470 (SP21P20_14920) yihA 1469306..1469893 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  AAA995_RS07475 (SP21P20_14930) clpX 1469902..1471134 (-) 1233 WP_000106349.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  AAA995_RS07480 - 1471166..1471336 (-) 171 WP_000442276.1 hypothetical protein -
  AAA995_RS07485 (SP21P20_14940) - 1471336..1471842 (-) 507 WP_000162444.1 dihydrofolate reductase -
  AAA995_RS07490 (SP21P20_14950) - 1471972..1472490 (-) 519 WP_000229856.1 Dps family protein -
  AAA995_RS07495 (SP21P20_14960) lytC 1472988..1474493 (-) 1506 WP_078139284.1 choline binding-anchored murein hydrolase LytC -
  AAA995_RS07500 (SP21P20_14970) tpiA 1474531..1475289 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  AAA995_RS07505 (SP21P20_14980) - 1475387..1476064 (-) 678 WP_000221614.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45816.38 Da        Isoelectric Point: 4.4550

>NTDB_id=107199 AAA995_RS07475 WP_000106349.1 1469902..1471134(-) (clpX) [Streptococcus pneumoniae strain 21P20]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRMGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=107199 AAA995_RS07475 WP_000106349.1 1469902..1471134(-) (clpX) [Streptococcus pneumoniae strain 21P20]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
CGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTGGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTTATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGTATCAATTTCCACGATACGCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAATCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAACGTGCCTTTTGCGATTGCGGATGCGACAGCTCTTACTGAGGCTGGTTATGTAGGTGAGGACGTGGAAAAT
ATCCTCCTTAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTATGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTCATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATTCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.965

98.049

0.559

Multiple sequence alignment