Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AAA995_RS01925 Genome accession   NZ_AP028877
Coordinates   364416..365105 (+) Length   229 a.a.
NCBI ID   WP_000518010.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21P20     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 359416..370105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA995_RS01900 (SP21P20_03720) gpsB 359525..359854 (+) 330 WP_000146522.1 cell division regulator GpsB -
  AAA995_RS01910 (SP21P20_03730) - 360340..361497 (+) 1158 WP_000711389.1 class I SAM-dependent RNA methyltransferase -
  AAA995_RS01915 (SP21P20_03740) mapZ 361510..362904 (+) 1395 WP_000039268.1 mid-cell-anchored protein MapZ -
  AAA995_RS01920 (SP21P20_03750) gndA 362980..364404 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  AAA995_RS01925 (SP21P20_03760) covR 364416..365105 (+) 690 WP_000518010.1 response regulator transcription factor Regulator
  AAA995_RS01930 (SP21P20_03770) cbpC 365203..366222 (+) 1020 WP_000771115.1 choline-binding protein CbpC -
  AAA995_RS01935 (SP21P20_03780) mvk 366344..367222 (+) 879 WP_000163315.1 mevalonate kinase -
  AAA995_RS01940 (SP21P20_03790) mvaD 367204..368157 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  AAA995_RS01945 (SP21P20_03800) - 368144..369151 (+) 1008 WP_000562430.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26862.16 Da        Isoelectric Point: 6.9836

>NTDB_id=107174 AAA995_RS01925 WP_000518010.1 364416..365105(+) (covR) [Streptococcus pneumoniae strain 21P20]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=107174 AAA995_RS01925 WP_000518010.1 364416..365105(+) (covR) [Streptococcus pneumoniae strain 21P20]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment