Detailed information    

insolico Bioinformatically predicted

Overview

Name   luxO   Type   Regulator
Locus tag   ACG4IY_RS09250 Genome accession   NZ_CP173268
Coordinates   2026973..2028340 (-) Length   455 a.a.
NCBI ID   WP_001888250.1    Uniprot ID   Q9KT84
Organism   Vibrio cholerae strain M646     
Function   promote HapR production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2021973..2033340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG4IY_RS09215 moaE 2022696..2023148 (-) 453 WP_000350081.1 molybdopterin synthase catalytic subunit MoaE -
  ACG4IY_RS09220 moaD 2023150..2023395 (-) 246 WP_000598590.1 molybdopterin synthase sulfur carrier subunit -
  ACG4IY_RS09225 moaC 2023392..2023871 (-) 480 WP_000080915.1 cyclic pyranopterin monophosphate synthase MoaC -
  ACG4IY_RS09230 moaB 2023882..2024394 (-) 513 WP_000509705.1 molybdenum cofactor biosynthesis protein B -
  ACG4IY_RS09235 moaA 2024454..2025443 (-) 990 WP_000068572.1 GTP 3',8-cyclase MoaA -
  ACG4IY_RS09240 - 2025749..2026639 (+) 891 WP_000061070.1 YvcK family protein -
  ACG4IY_RS09245 luxU 2026628..2026969 (-) 342 WP_001209531.1 quorum-sensing phosphorelay protein LuxU -
  ACG4IY_RS09250 luxO 2026973..2028340 (-) 1368 WP_001888250.1 quorum-sensing sigma-54 dependent transcriptional regulator LuxO Regulator
  ACG4IY_RS09255 uvrB 2028771..2030801 (-) 2031 WP_000029983.1 excinuclease ABC subunit UvrB -
  ACG4IY_RS09265 rsxA 2031683..2032264 (+) 582 WP_000141550.1 electron transport complex subunit RsxA -
  ACG4IY_RS09270 rsxB 2032264..2032851 (+) 588 WP_000104488.1 electron transport complex subunit RsxB -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50839.12 Da        Isoelectric Point: 5.5755

>NTDB_id=1071303 ACG4IY_RS09250 WP_001888250.1 2026973..2028340(-) (luxO) [Vibrio cholerae strain M646]
MVEDTASVAALYRSYLTPLDIDINIVGTGRDAIESIGRREPDLILLDLRLPDMTGMDVLYAVKEKSPDVPIVFMTAHGSI
DTAVEAMRHGAQDFLIKPCEADRLRVTVNNAIRKASKLKNDVDNKNQNYQGFIGSSQTMQAVYRTIDSAASSKASIFITG
ESGTGKEVCAEAIHAASKRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATERQGAAEAADGGTLFLDELCEMDLDL
QTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRARGDDVIEIAYSLLGF
MSKEEGKDFVRLSAEVVERFRQYEWPGNVRQLQNVLRNVVVLNEGREITLDMLPPPLNQMSAPINRALPLAHENKVSVHE
IFPLWMTEKQAIEQAIEACDGNIPRAATYLDVSPSTIYRKLQTWNEKVKEKEKER

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1071303 ACG4IY_RS09250 WP_001888250.1 2026973..2028340(-) (luxO) [Vibrio cholerae strain M646]
ATGGTAGAAGACACGGCGTCGGTGGCGGCGCTGTATCGTTCTTACCTCACACCGCTGGATATTGATATCAATATCGTGGG
TACCGGACGCGATGCCATCGAGAGTATTGGCCGTCGCGAGCCTGACTTAATCCTGCTGGATTTACGTTTGCCAGATATGA
CGGGGATGGACGTACTCTATGCAGTGAAAGAGAAATCACCGGATGTGCCTATCGTGTTTATGACCGCTCATGGTTCGATT
GATACGGCGGTTGAAGCCATGCGTCATGGTGCGCAAGACTTTTTGATCAAGCCGTGTGAAGCGGACCGACTGCGGGTCAC
AGTGAATAATGCGATTCGCAAAGCCTCGAAACTCAAAAACGATGTTGATAATAAAAATCAAAACTATCAAGGCTTTATTG
GTAGCAGTCAAACCATGCAGGCGGTGTACCGCACCATTGACTCTGCGGCGAGCAGCAAAGCCAGTATTTTTATTACCGGC
GAAAGTGGTACAGGTAAAGAAGTGTGCGCGGAAGCGATTCATGCCGCGAGCAAGCGTGGAGATAAGCCATTTATCGCCAT
CAACTGTGCGGCCATTCCGAAAGATCTGATTGAAAGTGAGTTGTTTGGTCACGTCAAAGGGGCTTTTACTGGGGCGGCGA
CTGAGCGTCAAGGCGCGGCAGAAGCGGCTGATGGGGGAACCCTCTTTTTGGATGAATTGTGCGAAATGGATCTGGATCTG
CAGACCAAACTTCTGCGCTTTATTCAGACAGGGACATTCCAAAAAGTCGGCTCTTCCAAAATGAAAAGCGTGGATGTGCG
TTTTGTGTGTGCAACGAACCGCGATCCGTGGAAGGAAGTGCAAGAAGGACGCTTTCGTGAAGACCTGTACTACCGCTTGT
ATGTGATCCCGCTGCATTTACCGCCATTGCGCGCGCGTGGTGATGATGTGATCGAGATTGCTTATTCACTGCTTGGCTTT
ATGTCCAAGGAAGAGGGCAAAGATTTTGTCCGTTTGTCGGCTGAAGTGGTGGAGCGTTTTCGCCAATACGAGTGGCCGGG
CAACGTGCGTCAATTGCAAAACGTTTTGCGCAACGTGGTTGTGCTCAATGAAGGTCGTGAAATCACCCTAGATATGCTGC
CTCCTCCTCTTAATCAAATGTCCGCGCCGATCAATCGGGCTTTACCGCTTGCGCATGAGAATAAAGTATCCGTGCATGAG
ATTTTTCCGCTGTGGATGACCGAAAAACAAGCCATTGAACAAGCCATCGAAGCGTGTGATGGCAACATTCCCCGTGCCGC
AACCTATCTGGATGTCAGCCCGTCAACCATCTATCGCAAGCTGCAAACTTGGAATGAAAAAGTGAAAGAAAAAGAGAAGG
AACGGTAA

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(404-442)

Sigma-54 interaction domain (Sigma54_activat)

(133-298)

Response regulator receiver domain (Response_reg)

(2-108)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9KT84

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  luxO Vibrio cholerae strain A1552

100

100

1
  pilR Pseudomonas aeruginosa PAK

38.274

99.341

0.38

Multiple sequence alignment