Detailed information
Bioinformatically predicted
Overview
| Name | pilL | Type | Machinery gene |
| Locus tag | ACIVJH_RS05525 | Genome accession | NZ_CP173226 |
| Coordinates | 1032268..1032741 (+) | Length | 157 a.a. |
| NCBI ID | WP_211305724.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain NCTC 8375 [B 5025] | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1032811..1070806 | 1032268..1032741 | flank | 70 |
Gene organization within MGE regions
Location: 1032268..1070806
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACIVJH_RS05525 | pilL | 1032268..1032741 (+) | 474 | WP_211305724.1 | PilX family type IV pilin | Machinery gene |
| ACIVJH_RS05530 | - | 1032811..1033119 (-) | 309 | WP_113852105.1 | AzlD family protein | - |
| ACIVJH_RS05535 | - | 1033116..1033824 (-) | 709 | Protein_1067 | AzlC family ABC transporter permease | - |
| ACIVJH_RS05540 | dut | 1033990..1034442 (+) | 453 | WP_113852107.1 | dUTP diphosphatase | - |
| ACIVJH_RS05545 | dapC | 1034520..1035707 (+) | 1188 | WP_113852108.1 | succinyldiaminopimelate transaminase | - |
| ACIVJH_RS05550 | yaaA | 1035863..1036642 (+) | 780 | WP_003687925.1 | peroxide stress protein YaaA | - |
| ACIVJH_RS05565 | - | 1037172..1038365 (+) | 1194 | WP_033910493.1 | phage integrase central domain-containing protein | - |
| ACIVJH_RS05570 | - | 1038721..1038990 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| ACIVJH_RS05575 | - | 1039185..1039868 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| ACIVJH_RS05580 | - | 1040149..1040415 (-) | 267 | Protein_1074 | hypothetical protein | - |
| ACIVJH_RS05585 | - | 1040526..1040741 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| ACIVJH_RS05590 | - | 1040793..1041284 (-) | 492 | WP_404376753.1 | siphovirus Gp157 family protein | - |
| ACIVJH_RS05595 | - | 1041281..1041463 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| ACIVJH_RS05600 | - | 1041603..1042289 (-) | 687 | WP_113852161.1 | phage replication initiation protein, NGO0469 family | - |
| ACIVJH_RS05605 | - | 1042358..1042519 (-) | 162 | WP_003693867.1 | hypothetical protein | - |
| ACIVJH_RS05610 | - | 1042516..1042791 (-) | 276 | WP_113852162.1 | NGO1622 family putative holin | - |
| ACIVJH_RS05615 | - | 1042944..1043276 (-) | 333 | WP_003695500.1 | hypothetical protein | - |
| ACIVJH_RS05620 | - | 1043889..1044107 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| ACIVJH_RS05625 | - | 1044124..1044483 (-) | 360 | WP_003694117.1 | hypothetical protein | - |
| ACIVJH_RS05630 | - | 1044484..1045023 (-) | 540 | WP_113852164.1 | Panacea domain-containing protein | - |
| ACIVJH_RS05635 | - | 1045183..1045887 (-) | 705 | WP_003702453.1 | helix-turn-helix transcriptional regulator | - |
| ACIVJH_RS05640 | - | 1046015..1046230 (+) | 216 | WP_223169978.1 | helix-turn-helix transcriptional regulator | - |
| ACIVJH_RS05645 | - | 1046310..1046465 (+) | 156 | WP_003689578.1 | hypothetical protein | - |
| ACIVJH_RS05650 | - | 1046442..1046630 (-) | 189 | WP_003691445.1 | hypothetical protein | - |
| ACIVJH_RS05655 | - | 1046803..1047030 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| ACIVJH_RS05660 | - | 1047148..1047615 (+) | 468 | WP_229692802.1 | hypothetical protein | - |
| ACIVJH_RS05665 | - | 1047710..1048213 (+) | 504 | WP_010360005.1 | hypothetical protein | - |
| ACIVJH_RS05670 | - | 1048210..1049568 (+) | 1359 | WP_003693467.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| ACIVJH_RS05675 | - | 1049585..1049836 (+) | 252 | WP_003693465.1 | hypothetical protein | - |
| ACIVJH_RS05680 | - | 1049850..1050344 (+) | 495 | WP_003693463.1 | DUF3310 domain-containing protein | - |
| ACIVJH_RS05685 | - | 1050806..1050955 (+) | 150 | WP_003692854.1 | hypothetical protein | - |
| ACIVJH_RS05690 | - | 1050984..1051694 (+) | 711 | WP_020996901.1 | RusA family crossover junction endodeoxyribonuclease | - |
| ACIVJH_RS05695 | - | 1051687..1051992 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| ACIVJH_RS05700 | - | 1051989..1052372 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| ACIVJH_RS05705 | - | 1052363..1052881 (+) | 519 | WP_003693459.1 | HNH endonuclease | - |
| ACIVJH_RS05710 | - | 1052946..1053368 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| ACIVJH_RS05715 | - | 1053368..1053907 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| ACIVJH_RS05720 | - | 1053888..1055162 (+) | 1275 | WP_047919159.1 | PBSX family phage terminase large subunit | - |
| ACIVJH_RS05725 | - | 1055147..1057414 (+) | 2268 | WP_225577699.1 | hypothetical protein | - |
| ACIVJH_RS05730 | - | 1057652..1058848 (+) | 1197 | WP_003693452.1 | hypothetical protein | - |
| ACIVJH_RS05735 | - | 1058845..1066152 (+) | 7308 | WP_003698268.1 | PLxRFG domain-containing protein | - |
| ACIVJH_RS05740 | - | 1066778..1068073 (+) | 1296 | WP_003693441.1 | DUF4043 family protein | - |
| ACIVJH_RS05745 | - | 1068132..1068605 (+) | 474 | WP_113852114.1 | hypothetical protein | - |
| ACIVJH_RS05750 | - | 1068611..1069096 (+) | 486 | WP_003693438.1 | hypothetical protein | - |
| ACIVJH_RS05755 | - | 1069093..1069746 (+) | 654 | WP_227719074.1 | hypothetical protein | - |
| ACIVJH_RS05760 | - | 1069769..1069918 (+) | 150 | WP_017146863.1 | hypothetical protein | - |
| ACIVJH_RS05765 | - | 1069955..1070806 (-) | 852 | WP_003693432.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 157 a.a. Molecular weight: 17472.27 Da Isoelectric Point: 9.7225
>NTDB_id=1070870 ACIVJH_RS05525 WP_211305724.1 1032268..1032741(+) (pilL) [Neisseria gonorrhoeae strain NCTC 8375 [B 5025]]
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDDNQIIKSKLEIFVSGYKM
NPKIAKKYSVSVAFANTEKPRAYRLVGVPKVGTGYTLSVWMNSVGDGYKCRDAASAQAYSETLSANTGCEAFSNRKK
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDDNQIIKSKLEIFVSGYKM
NPKIAKKYSVSVAFANTEKPRAYRLVGVPKVGTGYTLSVWMNSVGDGYKCRDAASAQAYSETLSANTGCEAFSNRKK
Nucleotide
Download Length: 474 bp
>NTDB_id=1070870 ACIVJH_RS05525 WP_211305724.1 1032268..1032741(+) (pilL) [Neisseria gonorrhoeae strain NCTC 8375 [B 5025]]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATTATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACGATAATCAGATCATCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTGGCATTTGCCAATACGGAAAAACCAAGGGCATACAGGTTGGTCGG
CGTTCCGAAGGTAGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCTGCCCAGGCCTATTCGGAGACCTTGTCCGCAAATACCGGCTGTGAAGCTTTCTCTAATCGTAAAAAATAG
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATTATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACGATAATCAGATCATCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTGGCATTTGCCAATACGGAAAAACCAAGGGCATACAGGTTGGTCGG
CGTTCCGAAGGTAGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCTGCCCAGGCCTATTCGGAGACCTTGTCCGCAAATACCGGCTGTGAAGCTTTCTCTAATCGTAAAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilL | Neisseria gonorrhoeae MS11 |
92.357 |
100 |
0.924 |
| pilX | Neisseria meningitidis 8013 |
87.898 |
100 |
0.879 |