Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACIVJH_RS03440 Genome accession   NZ_CP173226
Coordinates   632670..635816 (-) Length   1048 a.a.
NCBI ID   WP_404376554.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain NCTC 8375 [B 5025]     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 627670..640816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIVJH_RS03420 - 627738..628271 (-) 534 WP_003692498.1 hypothetical protein -
  ACIVJH_RS03425 - 629553..629942 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  ACIVJH_RS03430 - 630105..630484 (-) 380 Protein_656 VOC family protein -
  ACIVJH_RS03435 carA 630538..631671 (-) 1134 WP_113852110.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  ACIVJH_RS03440 pilC 632670..635816 (-) 3147 WP_404376554.1 PilC family type IV pilus tip adhesin Machinery gene
  ACIVJH_RS03445 apbC 636709..637788 (-) 1080 WP_113852111.1 iron-sulfur cluster carrier protein ApbC -
  ACIVJH_RS03455 - 638154..638663 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  ACIVJH_RS03460 nadR 639004..639444 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  ACIVJH_RS03465 hpaC 639559..640059 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  ACIVJH_RS03470 murU 640075..640770 (+) 696 WP_003687300.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -

Sequence

Protein


Download         Length: 1048 a.a.        Molecular weight: 115297.77 Da        Isoelectric Point: 9.8791

>NTDB_id=1070854 ACIVJH_RS03440 WP_404376554.1 632670..635816(-) (pilC) [Neisseria gonorrhoeae strain NCTC 8375 [B 5025]]
MNKTLKRQVFRHTALYAAILMFSHTGGGGAMAQTHKYAIIMNERKQPEVKWDGQYQKSQLREKDGERKFIYTNQKYWSGQ
QSNFISFDNTDTLVSRQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIHTTRAGLAGYAYTGIRCGHARDCPKLT
YKTRFSFDNPDLAKTGGGLLDRHTEPSRENSPIYKLKDHPWLGVSFNLGAEGTAKDGRSSSRLISSFNETNSNNNLVYTT
EGRDISLGNWQSESTAVAYYLNAKLHLLDKKKIKDITGKTVQLGVLKPSIDVKTQNTGFAGWLNFWSKWDIKDNGQIPVK
LGLPEVKAGRCTNAAHPNLKAKPLSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGRHSL
AALNARDIKSREPNFNSRQTVIRLPGGVYKINPGKNGGRVAGFNGDDGKNDTFGIYKDRLVTPEVDEWSNILLPWTARYY
GNDDIFKTFNQPNSKTQNGKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVGGYLATAANDGMVHLFKRNGTDQRGYE
LKLSYIPGTMERKDIENQDSTLAKELRTFAEQGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTK
IDSNPVGVSMFDVQNDKNNNNNKNDSNRVKLGYTVGTPQIGKIRNGKYAAFLASGYAAKDIASQENKTALYVYDLKDTLG
TPITKIEVNDGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSNSDPSKWSVSTIFEGGKPITSAPAVSRLADKRV
VIFGTGSDLSEEDVVGTNPQYIYGIFDDDKPTVNVKVTNGTGGGLLEQVLSEENKTLFLNKKSDGSGSKGWVVKLKEGQR
VTVKPTVVLRTAFVTIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPDNQVAQYSGHQKMNGKSIPIGCMWKNGK
TVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIKR
LSWREVFF

Nucleotide


Download         Length: 3147 bp        

>NTDB_id=1070854 ACIVJH_RS03440 WP_404376554.1 632670..635816(-) (pilC) [Neisseria gonorrhoeae strain NCTC 8375 [B 5025]]
ATGAATAAAACTTTGAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGATGGGC
AATATCAAAAATCACAATTAAGGGAAAAAGACGGGGAACGCAAATTTATCTATACGAACCAGAAATACTGGTCGGGTCAA
CAAAGCAATTTTATCTCATTCGACAATACCGATACCCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCAC
CTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATTGGATTC
ATACCACCCGGGCCGGGCTGGCAGGCTACGCCTACACCGGTATCCGTTGCGGACATGCCCGAGACTGTCCCAAACTTACC
TATAAAACCCGATTTTCCTTCGATAATCCCGACTTGGCAAAAACAGGAGGCGGGCTGCTGGATAGGCACACAGAGCCAAG
CCGCGAAAATTCGCCCATTTACAAATTGAAAGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCG
CCAAAGATGGCAGATCATCCAGCAGATTGATATCTTCTTTTAATGAAACGAATAGTAATAACAACCTCGTCTATACCACG
GAAGGCCGCGATATTTCCTTGGGCAACTGGCAGAGCGAAAGTACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCACCT
GCTGGACAAAAAAAAGATTAAAGATATCACCGGCAAAACAGTGCAGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGA
CACAAAATACGGGGTTTGCCGGCTGGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAG
CTCGGCCTGCCGGAAGTCAAAGCCGGGCGCTGCACCAACGCCGCCCACCCCAATCTCAAGGCCAAACCCCTTTCGCCGGC
ACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACC
CCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGGCATTCCCTC
GCCGCTTTGAATGCGCGGGATATCAAAAGCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGG
CGTGTACAAGATCAACCCGGGCAAGAACGGCGGCCGGGTCGCGGGTTTTAATGGCGATGACGGCAAAAACGACACTTTCG
GCATCTACAAGGACAGGCTCGTCACACCTGAGGTCGACGAGTGGAGCAACATACTGCTGCCTTGGACGGCCCGGTATTAC
GGTAATGACGATATATTTAAAACATTCAACCAACCAAACAGCAAAACACAAAACGGCAAAAAACAATACAGCCAAAAATA
CCGCATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCG
GCGGGTATTTGGCAACCGCCGCGAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAA
CTGAAGCTCAGCTACATCCCGGGTACGATGGAGCGTAAGGATATTGAAAACCAAGACTCCACCCTCGCCAAAGAGCTGCG
CACCTTTGCCGAACAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACC
AAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTGGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAA
ATCGACAGCAACCCGGTCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAACAATAAGAATGACAGTAA
TCGCGTGAAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAATCCGCAACGGCAAATACGCCGCCTTCCTCGCCT
CCGGTTATGCGGCTAAAGATATTGCCAGCCAAGAAAATAAAACCGCGCTGTATGTATATGATTTGAAAGACACCTTAGGT
ACGCCGATTACAAAAATCGAAGTGAATGACGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGG
CACGGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCAATTCCGATCCTAGTAAAT
GGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTG
GTCATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTACGAATCCACAATATATTTACGGTATCTTTGA
CGACGATAAGCCGACGGTTAATGTAAAGGTAACAAACGGCACGGGAGGCGGGCTGCTCGAGCAAGTGCTTAGTGAGGAAA
ATAAAACCTTATTCCTGAACAAGAAATCCGACGGTTCGGGCAGTAAGGGGTGGGTAGTGAAGCTGAAGGAAGGACAGCGC
GTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTCACCATCCGCAGCTATACGGGTAATGACAAATGCGGCGC
GCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATA
ACCAGGTTGCGCAATATTCCGGCCATCAGAAAATGAACGGCAAGTCCATCCCCATAGGCTGTATGTGGAAAAACGGCAAA
ACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGATTTCCC
CGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCT
CCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGTCCGATGTGCGGTATCAAACGC
TTAAGCTGGCGTGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(522-860)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

69.688

100

0.704

Multiple sequence alignment