Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   ACIFYW_RS10725 Genome accession   NZ_CP173026
Coordinates   2409368..2409979 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain SPH 24-01     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2404368..2414979
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIFYW_RS10705 (ACIFYW_10705) - 2404704..2405621 (-) 918 WP_404272591.1 ABC transporter ATP-binding protein -
  ACIFYW_RS10710 (ACIFYW_10710) - 2406002..2407648 (-) 1647 WP_230662668.1 SulP family inorganic anion transporter -
  ACIFYW_RS10715 (ACIFYW_10715) can 2407796..2408464 (+) 669 WP_001114117.1 carbonate dehydratase -
  ACIFYW_RS10720 (ACIFYW_10720) hpt 2408539..2409072 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  ACIFYW_RS10725 (ACIFYW_10725) hapR 2409368..2409979 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  ACIFYW_RS10730 (ACIFYW_10730) rsmI 2410189..2411055 (-) 867 WP_000131547.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  ACIFYW_RS10735 (ACIFYW_10735) - 2411125..2412930 (+) 1806 WP_404272866.1 penicillin-binding protein activator -
  ACIFYW_RS10740 (ACIFYW_10740) - 2412917..2413285 (+) 369 WP_057557505.1 YraN family protein -
  ACIFYW_RS10745 (ACIFYW_10745) - 2413289..2413879 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  ACIFYW_RS10750 (ACIFYW_10750) - 2413882..2414451 (+) 570 WP_000836325.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=1070045 ACIFYW_RS10725 WP_000340100.1 2409368..2409979(+) (hapR) [Vibrio cholerae strain SPH 24-01]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=1070045 ACIFYW_RS10725 WP_000340100.1 2409368..2409979(+) (hapR) [Vibrio cholerae strain SPH 24-01]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAATTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment