Detailed information NTG1069968

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: ACG2K1_RS10510
• Genome accession: NZ_CP173024
• Coordinates: 2106141..2107004 (-)
• Length: 287 a.a.
• NCBI ID: WP_009425281.1
• Uniprot ID: L1NWY0
• Organism: Neisseria sp. 23W00296
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2101141..2112004

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACG2K1_RS10475 (ACG2K1_10475)	-	2101519..2102406 (+)	888	WP_395429233.1	prephenate dehydrogenase	-
ACG2K1_RS10480 (ACG2K1_10480)	-	2102735..2103145 (-)	411	WP_157058124.1	DUF2846 domain-containing protein	-
ACG2K1_RS10485 (ACG2K1_10485)	-	2103269..2103790 (-)	522	WP_402837186.1	hypothetical protein	-
ACG2K1_RS10490 (ACG2K1_10490)	-	2103835..2104443 (-)	609	WP_009425277.1	HI_0552 family protein	-
ACG2K1_RS10495 (ACG2K1_10495)	-	2104568..2104765 (-)	198	WP_009425278.1	DNA gyrase inhibitor YacG	-
ACG2K1_RS10500 (ACG2K1_10500)	zapD	2104766..2105527 (-)	762	WP_009425279.1	cell division protein ZapD	-
ACG2K1_RS10505 (ACG2K1_10505)	coaE	2105524..2106144 (-)	621	WP_009425280.1	dephospho-CoA kinase	-
ACG2K1_RS10510 (ACG2K1_10510)	pilD	2106141..2107004 (-)	864	WP_009425281.1	A24 family peptidase	Machinery gene
ACG2K1_RS10515 (ACG2K1_10515)	pilG	2107032..2108255 (-)	1224	WP_009425282.1	type II secretion system F family protein	Machinery gene
ACG2K1_RS10520 (ACG2K1_10520)	pilF	2108273..2109946 (-)	1674	WP_395429234.1	type IV-A pilus assembly ATPase PilB	Machinery gene
ACG2K1_RS10525 (ACG2K1_10525)	-	2110086..2111675 (-)	1590	WP_009425284.1	inorganic phosphate transporter	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 31296.27 Da
• Isoelectric Point: 8.5788

>NTDB_id=1069968 ACG2K1_RS10510 WP_009425281.1 2106141..2107004(-) (pilD) [Neisseria sp. 23W00296]
MTEYYAPLVIPISVILGLLVGSFLNVVIYRVPVMMERGWTLFSKEHLGIELTDEEKQPFSLTRPPSRCPKCGNRVRPWQN
IPVVSYLLLKGKCGHCHTHISARYPAVEVLTAVVFGIVAACYGWSWITLTGLVFTGFLVALAFIDADTQYLPDELTIPLV
WLGLLAAYGGSGLVTLQQSVMGAVCGYLSLWLLNRLHKQIRGIDGMGGGDFKLLAALGAWLGAAVLPVVVFVAAVVGIVS
ALIMKVRQSQPMAFGPCLIIAGWIVFVTHDKVLAGVRWWLHMSGFSA

Nucleotide

• Length: 864 bp

>NTDB_id=1069968 ACG2K1_RS10510 WP_009425281.1 2106141..2107004(-) (pilD) [Neisseria sp. 23W00296]
ATGACGGAATATTATGCCCCTTTGGTCATTCCCATCTCGGTAATTCTCGGCCTGCTGGTCGGTAGTTTTCTCAATGTCGT
GATTTACCGCGTTCCCGTGATGATGGAACGCGGGTGGACTCTGTTTTCCAAAGAGCATTTGGGAATCGAGCTGACCGATG
AGGAAAAGCAGCCGTTCAGTCTGACCCGGCCGCCGTCGCGCTGTCCGAAATGCGGTAACCGGGTCAGGCCGTGGCAGAAC
ATACCGGTTGTCAGCTACTTGCTGTTGAAAGGCAAATGCGGCCATTGCCATACCCATATCAGTGCCCGTTATCCCGCTGT
CGAAGTATTGACGGCCGTTGTGTTCGGCATTGTTGCCGCTTGTTACGGCTGGTCTTGGATAACGCTGACAGGCTTGGTGT
TTACGGGTTTCTTGGTGGCTTTGGCCTTTATCGATGCGGATACGCAATATCTGCCTGACGAGCTGACCATTCCTCTGGTT
TGGCTGGGTTTGCTTGCGGCTTATGGCGGCAGCGGCTTGGTTACCTTGCAGCAGTCTGTCATGGGCGCGGTATGCGGCTA
TCTCAGCTTATGGCTGTTAAACCGGCTTCATAAGCAGATTCGCGGAATTGACGGCATGGGCGGAGGCGATTTCAAGCTTT
TGGCCGCATTGGGTGCGTGGCTTGGCGCGGCGGTTTTGCCCGTTGTCGTTTTTGTTGCGGCCGTTGTCGGTATTGTTTCT
GCCCTCATTATGAAAGTCAGACAAAGCCAGCCGATGGCTTTCGGCCCCTGCCTGATTATTGCCGGCTGGATTGTTTTCGT
CACGCATGACAAAGTTCTGGCAGGCGTGCGCTGGTGGCTGCATATGTCGGGTTTTTCGGCATGA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (132-241)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (15-120)

3D structure

• AlphaFold DB: L1NWY0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	60	95.819	0.575
pilD	Vibrio campbellii strain DS40M4	45.455	95.819	0.436
pilD	Vibrio cholerae strain A1552	44	95.819	0.422
pilD	Acinetobacter baumannii D1279779	44.828	90.941	0.408
pilD	Acinetobacter nosocomialis M2	44.444	90.941	0.404