Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ACF1RT_RS07810 Genome accession   NZ_CP172847
Coordinates   1567613..1568914 (-) Length   433 a.a.
NCBI ID   WP_002269523.1    Uniprot ID   -
Organism   Streptococcus mutans strain DPC6143     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1562613..1573914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF1RT_RS07785 (ACF1RT_07785) - 1562671..1563306 (+) 636 WP_002263021.1 hypothetical protein -
  ACF1RT_RS07790 (ACF1RT_07790) - 1563386..1565086 (-) 1701 WP_002263022.1 zinc ribbon domain-containing protein -
  ACF1RT_RS07795 (ACF1RT_07795) - 1565106..1566200 (-) 1095 WP_002300280.1 hypothetical protein -
  ACF1RT_RS07800 (ACF1RT_07800) hpf 1566324..1566872 (-) 549 WP_002269521.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACF1RT_RS07805 (ACF1RT_07805) - 1566951..1567616 (-) 666 WP_002269522.1 ComF family protein -
  ACF1RT_RS07810 (ACF1RT_07810) comFA/cflA 1567613..1568914 (-) 1302 WP_002269523.1 DEAD/DEAH box helicase Machinery gene
  ACF1RT_RS07815 (ACF1RT_07815) - 1568987..1569616 (+) 630 WP_002263027.1 YigZ family protein -
  ACF1RT_RS07820 (ACF1RT_07820) cysK 1569707..1570633 (+) 927 WP_002263028.1 cysteine synthase A -
  ACF1RT_RS07825 (ACF1RT_07825) - 1570967..1572058 (-) 1092 WP_002267044.1 glycerol dehydrogenase -
  ACF1RT_RS07830 (ACF1RT_07830) - 1572097..1572765 (-) 669 WP_002293872.1 fructose-6-phosphate aldolase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49441.62 Da        Isoelectric Point: 10.0270

>NTDB_id=1069103 ACF1RT_RS07810 WP_002269523.1 1567613..1568914(-) (comFA/cflA) [Streptococcus mutans strain DPC6143]
MENLENYYGRLLAENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRGKLPRSFLQQIRIQRQTQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1069103 ACF1RT_RS07810 WP_002269523.1 1567613..1568914(-) (comFA/cflA) [Streptococcus mutans strain DPC6143]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGGCCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGGTAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGACTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACCTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAGATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-194)

Helicase conserved C-terminal domain (Helicase_C)

(296-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae D39

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae R6

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae TIGR4

59.251

98.614

0.584
  comFA/cflA Streptococcus mitis NCTC 12261

58.548

98.614

0.577
  comFA/cflA Streptococcus mitis SK321

58.08

98.614

0.573
  comFA Lactococcus lactis subsp. cremoris KW2

51.777

90.993

0.471
  comFA Latilactobacillus sakei subsp. sakei 23K

39.202

98.383

0.386

Multiple sequence alignment