Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   AADG46_RS01505 Genome accession   NZ_AP028804
Coordinates   287670..288281 (-) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain VN152     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 282670..293281
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AADG46_RS01480 (VNVC001_02430) - 283196..283765 (-) 570 WP_000836325.1 BON domain-containing protein -
  AADG46_RS01485 (VNVC001_02440) - 283768..284358 (-) 591 WP_000887295.1 phosphoheptose isomerase -
  AADG46_RS01490 (VNVC001_02450) - 284362..284685 (-) 324 WP_000718567.1 YraN family protein -
  AADG46_RS01495 (VNVC001_02460) - 284717..286522 (-) 1806 WP_001015477.1 penicillin-binding protein activator -
  AADG46_RS01500 (VNVC001_02470) rsmI 286592..287458 (+) 867 WP_148529376.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  AADG46_RS01505 (VNVC001_02490) hapR 287670..288281 (-) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  AADG46_RS01510 (VNVC001_02500) hpt 288577..289110 (+) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  AADG46_RS01515 (VNVC001_02510) can 289185..289853 (-) 669 WP_001114117.1 carbonate dehydratase -
  AADG46_RS01520 (VNVC001_02520) - 290001..291647 (+) 1647 WP_337028214.1 SulP family inorganic anion transporter -
  AADG46_RS01525 (VNVC001_02530) - 292028..292945 (+) 918 WP_340701884.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=106902 AADG46_RS01505 WP_000340100.1 287670..288281(-) (hapR) [Vibrio cholerae strain VN152]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=106902 AADG46_RS01505 WP_000340100.1 287670..288281(-) (hapR) [Vibrio cholerae strain VN152]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAATTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment