Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACHZEV_RS04615 Genome accession   NZ_CP172401
Coordinates   978420..978989 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus strain M22.2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 973420..983989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHZEV_RS04575 (ACHZEV_04575) - 973894..974502 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  ACHZEV_RS04580 (ACHZEV_04580) rplL 974677..975045 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACHZEV_RS04585 (ACHZEV_04585) rplJ 975088..975588 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACHZEV_RS04590 (ACHZEV_04590) rplA 975860..976552 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACHZEV_RS04595 (ACHZEV_04595) rplK 976760..977182 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACHZEV_RS04600 (ACHZEV_04600) nusG 977363..977911 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACHZEV_RS04605 (ACHZEV_04605) secE 977924..978106 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACHZEV_RS04610 (ACHZEV_04610) rpmG 978162..978305 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACHZEV_RS04615 (ACHZEV_04615) sigH 978420..978989 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACHZEV_RS04620 (ACHZEV_04620) - 979071..979595 (-) 525 WP_000664738.1 NYN domain-containing protein -
  ACHZEV_RS04625 (ACHZEV_04625) rlmB 979595..980341 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACHZEV_RS04630 (ACHZEV_04630) - 980349..980753 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  ACHZEV_RS04635 (ACHZEV_04635) cysS 980746..982146 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  ACHZEV_RS04640 (ACHZEV_04640) cysE 982130..982777 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1067344 ACHZEV_RS04615 WP_000872879.1 978420..978989(-) (sigH) [Staphylococcus aureus strain M22.2]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1067344 ACHZEV_RS04615 WP_000872879.1 978420..978989(-) (sigH) [Staphylococcus aureus strain M22.2]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment