Detailed information    

insolico Bioinformatically predicted

Overview

Name   CJE1441   Type   Regulator
Locus tag   ACH6FZ_RS06405 Genome accession   NZ_CP172361
Coordinates   1228715..1229368 (+) Length   217 a.a.
NCBI ID   WP_011049930.1    Uniprot ID   A0A3X8NAQ4
Organism   Campylobacter jejuni strain YH023     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1210600..1264911 1228715..1229368 within 0


Gene organization within MGE regions


Location: 1210600..1264911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH6FZ_RS06260 (ACH6FZ_06260) - 1210600..1211793 (-) 1194 WP_002853860.1 murein hydrolase activator EnvC -
  ACH6FZ_RS06265 (ACH6FZ_06265) - 1211790..1212596 (-) 807 WP_002853622.1 FtsX-like permease family protein -
  ACH6FZ_RS06270 (ACH6FZ_06270) - 1212583..1213248 (-) 666 WP_002853534.1 cell division ATP-binding protein FtsE -
  ACH6FZ_RS06275 (ACH6FZ_06275) trmB 1213318..1214496 (-) 1179 WP_002858203.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  ACH6FZ_RS06280 (ACH6FZ_06280) - 1214496..1215731 (-) 1236 WP_014516824.1 fibronectin type III domain-containing protein -
  ACH6FZ_RS06285 (ACH6FZ_06285) - 1215676..1216644 (-) 969 WP_002858282.1 RluA family pseudouridine synthase -
  ACH6FZ_RS06290 (ACH6FZ_06290) mrdB 1216722..1217822 (+) 1101 WP_002853654.1 FtsW/RodA/SpoVE family cell cycle protein -
  ACH6FZ_RS06300 (ACH6FZ_06300) - 1218161..1219336 (+) 1176 WP_002787311.1 site-specific integrase -
  ACH6FZ_RS06305 (ACH6FZ_06305) - 1219333..1219539 (-) 207 WP_002787309.1 AlpA family transcriptional regulator -
  ACH6FZ_RS06310 (ACH6FZ_06310) - 1219541..1219894 (-) 354 WP_002787307.1 hypothetical protein -
  ACH6FZ_RS06315 (ACH6FZ_06315) - 1219912..1220667 (-) 756 WP_002787306.1 site-specific DNA-methyltransferase -
  ACH6FZ_RS06320 (ACH6FZ_06320) - 1220645..1220911 (-) 267 WP_002787304.1 hypothetical protein -
  ACH6FZ_RS06325 (ACH6FZ_06325) - 1220895..1221266 (-) 372 WP_002858334.1 hypothetical protein -
  ACH6FZ_RS06330 (ACH6FZ_06330) - 1221267..1221491 (-) 225 WP_002787300.1 hypothetical protein -
  ACH6FZ_RS06335 (ACH6FZ_06335) - 1221500..1222261 (-) 762 WP_002787298.1 hypothetical protein -
  ACH6FZ_RS06340 (ACH6FZ_06340) - 1222198..1222512 (-) 315 WP_002787295.1 hypothetical protein -
  ACH6FZ_RS06345 (ACH6FZ_06345) - 1222591..1222911 (-) 321 WP_002787293.1 hypothetical protein -
  ACH6FZ_RS06350 (ACH6FZ_06350) - 1223298..1223534 (-) 237 WP_002787289.1 hypothetical protein -
  ACH6FZ_RS06355 (ACH6FZ_06355) - 1223548..1224315 (-) 768 WP_002787287.1 hypothetical protein -
  ACH6FZ_RS06360 (ACH6FZ_06360) - 1224453..1224683 (-) 231 WP_002787283.1 hypothetical protein -
  ACH6FZ_RS06365 (ACH6FZ_06365) - 1224649..1224912 (-) 264 WP_002787281.1 hypothetical protein -
  ACH6FZ_RS06370 (ACH6FZ_06370) - 1224969..1225256 (-) 288 WP_002787279.1 YopX family protein -
  ACH6FZ_RS06375 (ACH6FZ_06375) - 1225309..1225809 (-) 501 WP_230094574.1 phage antirepressor KilAC domain-containing protein -
  ACH6FZ_RS06380 (ACH6FZ_06380) - 1225815..1226039 (-) 225 WP_002858343.1 Rha family transcriptional regulator -
  ACH6FZ_RS06385 (ACH6FZ_06385) - 1226470..1226754 (-) 285 WP_002788580.1 hypothetical protein -
  ACH6FZ_RS06390 (ACH6FZ_06390) - 1226751..1226954 (-) 204 WP_002870299.1 hypothetical protein -
  ACH6FZ_RS06395 (ACH6FZ_06395) - 1227159..1227812 (+) 654 WP_002870336.1 hypothetical protein -
  ACH6FZ_RS06400 (ACH6FZ_06400) - 1228047..1228709 (+) 663 WP_002870274.1 S24/S26 family peptidase -
  ACH6FZ_RS06405 (ACH6FZ_06405) CJE1441 1228715..1229368 (+) 654 WP_011049930.1 DNA/RNA non-specific endonuclease Regulator
  ACH6FZ_RS06410 (ACH6FZ_06410) - 1229385..1229666 (+) 282 WP_002870263.1 PLDc N-terminal domain-containing protein -
  ACH6FZ_RS06415 (ACH6FZ_06415) - 1229680..1229877 (-) 198 WP_002913413.1 hypothetical protein -
  ACH6FZ_RS06420 (ACH6FZ_06420) - 1229795..1230214 (-) 420 WP_002870261.1 hypothetical protein -
  ACH6FZ_RS06425 (ACH6FZ_06425) - 1230443..1230904 (-) 462 WP_002870260.1 DUF5675 family protein -
  ACH6FZ_RS06430 (ACH6FZ_06430) - 1230953..1232236 (-) 1284 WP_002788854.1 hypothetical protein -
  ACH6FZ_RS06435 (ACH6FZ_06435) - 1232233..1232607 (-) 375 WP_395766093.1 DUF1353 domain-containing protein -
  ACH6FZ_RS06440 (ACH6FZ_06440) - 1232600..1232983 (-) 384 WP_002869963.1 hypothetical protein -
  ACH6FZ_RS06445 (ACH6FZ_06445) - 1232980..1233615 (-) 636 WP_002789149.1 DUF4376 domain-containing protein -
  ACH6FZ_RS06450 (ACH6FZ_06450) - 1233628..1234077 (-) 450 WP_002896804.1 hypothetical protein -
  ACH6FZ_RS06455 (ACH6FZ_06455) - 1234079..1235644 (-) 1566 WP_395766094.1 coiled-coil domain-containing protein -
  ACH6FZ_RS06460 (ACH6FZ_06460) - 1235637..1236269 (-) 633 WP_283151889.1 hypothetical protein -
  ACH6FZ_RS06465 (ACH6FZ_06465) - 1236266..1236583 (-) 318 WP_002788295.1 head-tail adaptor protein -
  ACH6FZ_RS06470 (ACH6FZ_06470) - 1236596..1237033 (-) 438 WP_044778997.1 phage gp6-like head-tail connector protein -
  ACH6FZ_RS06475 (ACH6FZ_06475) - 1237030..1237281 (-) 252 WP_002788291.1 hypothetical protein -
  ACH6FZ_RS06480 (ACH6FZ_06480) - 1237292..1238458 (-) 1167 WP_002788288.1 phage major capsid protein -
  ACH6FZ_RS06485 (ACH6FZ_06485) - 1238475..1239032 (-) 558 WP_002788287.1 HK97 family phage prohead protease -
  ACH6FZ_RS06490 (ACH6FZ_06490) - 1239118..1239987 (-) 870 WP_395766095.1 hypothetical protein -
  ACH6FZ_RS06495 (ACH6FZ_06495) - 1239998..1245724 (-) 5727 WP_395766096.1 hypothetical protein -
  ACH6FZ_RS06500 (ACH6FZ_06500) - 1245784..1246122 (+) 339 WP_038851012.1 hypothetical protein -
  ACH6FZ_RS06505 (ACH6FZ_06505) - 1246114..1246329 (-) 216 WP_002788282.1 hypothetical protein -
  ACH6FZ_RS06510 (ACH6FZ_06510) - 1246410..1246766 (-) 357 WP_002788281.1 hypothetical protein -
  ACH6FZ_RS06515 (ACH6FZ_06515) - 1246763..1247743 (-) 981 WP_038851013.1 hypothetical protein -
  ACH6FZ_RS06520 (ACH6FZ_06520) - 1247915..1248265 (-) 351 WP_002788276.1 hypothetical protein -
  ACH6FZ_RS06525 (ACH6FZ_06525) - 1248266..1248808 (-) 543 WP_002800770.1 HK97 gp10 family phage protein -
  ACH6FZ_RS06530 (ACH6FZ_06530) - 1248805..1249977 (-) 1173 WP_002788272.1 phage portal protein -
  ACH6FZ_RS06535 (ACH6FZ_06535) - 1250136..1250570 (-) 435 WP_395766097.1 type II toxin-antitoxin system PemK/MazF family toxin -
  ACH6FZ_RS06540 (ACH6FZ_06540) - 1250625..1252250 (-) 1626 WP_002913304.1 terminase large subunit -
  ACH6FZ_RS06545 (ACH6FZ_06545) - 1252254..1252892 (-) 639 WP_002913306.1 P27 family phage terminase small subunit -
  ACH6FZ_RS06550 (ACH6FZ_06550) - 1253143..1253493 (-) 351 WP_002869973.1 HNH endonuclease -
  ACH6FZ_RS06555 (ACH6FZ_06555) - 1253480..1253770 (-) 291 WP_002788257.1 hypothetical protein -
  ACH6FZ_RS06565 (ACH6FZ_06565) ktrB 1254514..1255857 (+) 1344 WP_002858357.1 TrkH family potassium uptake protein -
  ACH6FZ_RS06570 (ACH6FZ_06570) ktrA 1255868..1256518 (+) 651 WP_002853664.1 TrkA family potassium uptake protein -
  ACH6FZ_RS06575 (ACH6FZ_06575) - 1256515..1257186 (-) 672 WP_002857885.1 MqnA/MqnD/SBP family protein -
  ACH6FZ_RS06580 (ACH6FZ_06580) upp 1257192..1257818 (-) 627 WP_002858427.1 uracil phosphoribosyltransferase -
  ACH6FZ_RS06585 (ACH6FZ_06585) - 1257815..1259050 (-) 1236 WP_002854063.1 malic enzyme-like NAD(P)-binding protein -
  ACH6FZ_RS06590 (ACH6FZ_06590) gltX 1259052..1260443 (-) 1392 WP_002858284.1 glutamate--tRNA ligase -
  ACH6FZ_RS06595 (ACH6FZ_06595) salC 1260508..1261323 (+) 816 WP_002856474.1 peptidylprolyl isomerase SalC -
  ACH6FZ_RS06600 (ACH6FZ_06600) accC 1261361..1262692 (-) 1332 WP_002858001.1 acetyl-CoA carboxylase biotin carboxylase subunit -
  ACH6FZ_RS06605 (ACH6FZ_06605) accB 1262694..1263149 (-) 456 WP_002853623.1 acetyl-CoA carboxylase biotin carboxyl carrier protein -
  ACH6FZ_RS06610 (ACH6FZ_06610) dcd 1263297..1263857 (+) 561 WP_002854086.1 dCTP deaminase -
  ACH6FZ_RS06615 (ACH6FZ_06615) pseB 1263907..1264911 (+) 1005 WP_002858028.1 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 25531.02 Da        Isoelectric Point: 9.8742

>NTDB_id=1066786 ACH6FZ_RS06405 WP_011049930.1 1228715..1229368(+) (CJE1441) [Campylobacter jejuni strain YH023]
MKKLIILSLLSTLAFADYTQYKPSEDFAKYFTKQNCSQVLDKFYYINCYDYSLKGTKAVAYRLEADNLKGEQIKKRPRFE
DDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQRSTFLMSNITPQNPQINQRVWNKIEKRERQVALKLGSLEVL
NLVNYDNNPQRIKNNIAIPSSYTKILKGDNFKECYQVPNHDVENENLRIYKVKCDNF

Nucleotide


Download         Length: 654 bp        

>NTDB_id=1066786 ACH6FZ_RS06405 WP_011049930.1 1228715..1229368(+) (CJE1441) [Campylobacter jejuni strain YH023]
ATGAAAAAACTTATAATCTTATCTTTATTATCCACTCTAGCTTTTGCTGATTATACACAATACAAACCAAGCGAAGATTT
TGCCAAGTATTTTACTAAACAAAACTGCTCACAAGTTTTGGATAAATTTTATTATATTAATTGTTATGATTATTCTTTAA
AAGGCACTAAAGCCGTAGCTTATAGATTAGAAGCGGATAATTTAAAAGGCGAACAAATCAAAAAACGCCCACGCTTTGAA
GATGATACAAATATTCCTAAAAAATACCGCACCACATGGAGTGATTATAAAAACAGCGGTTACGACAGGGGACACACTCT
TTCTAATGCTTCAATGAGAAAAACAACTCAAGCTCAAAGAAGCACTTTTTTAATGAGCAACATTACTCCACAAAATCCAC
AAATCAATCAAAGAGTTTGGAATAAAATTGAAAAAAGAGAAAGACAAGTAGCTTTAAAGCTTGGAAGTTTAGAAGTTTTA
AATTTGGTTAATTATGACAATAATCCACAAAGAATAAAAAACAATATTGCCATTCCAAGCTCTTACACTAAGATTTTAAA
AGGTGATAATTTTAAAGAATGTTACCAAGTGCCTAATCACGATGTAGAAAATGAGAATTTAAGAATATATAAAGTAAAAT
GTGACAATTTTTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(27-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3X8NAQ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  CJE1441 Campylobacter jejuni RM1221

100

100

1
  CJE0566 Campylobacter jejuni RM1221

91.163

99.078

0.903

Multiple sequence alignment