Detailed information NTG1066193

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACF0KO_RS02940
• Genome accession: NZ_CP172307
• Coordinates: 668648..669988 (+)
• Length: 446 a.a.
• NCBI ID: WP_064031613.1
• Uniprot ID: A0A177N1L6
• Organism: Methylomonas sp. 2B
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 663648..674988

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF0KO_RS02925 (ACF0KO_02925)	sucD	664857..665729 (-)	873	WP_064031616.1	succinate--CoA ligase subunit alpha	-
ACF0KO_RS02930 (ACF0KO_02930)	sucC	665729..666898 (-)	1170	WP_064031615.1	ADP-forming succinate--CoA ligase subunit beta	-
ACF0KO_RS02935 (ACF0KO_02935)	-	667026..668651 (+)	1626	WP_064031614.1	PAS domain-containing sensor histidine kinase	-
ACF0KO_RS02940 (ACF0KO_02940)	pilR	668648..669988 (+)	1341	WP_064031613.1	sigma-54 dependent transcriptional regulator	Regulator
ACF0KO_RS02945 (ACF0KO_02945)	-	670027..670491 (-)	465	WP_064031612.1	hypothetical protein	-
ACF0KO_RS02950 (ACF0KO_02950)	-	670624..672459 (-)	1836	WP_064031611.1	EAL domain-containing protein	-
ACF0KO_RS02955 (ACF0KO_02955)	-	672642..673487 (+)	846	WP_064031610.1	HDOD domain-containing protein	-

Sequence

Protein

• Length: 446 a.a.
• Molecular weight: 49089.68 Da
• Isoelectric Point: 6.5107

>NTDB_id=1066193 ACF0KO_RS02940 WP_064031613.1 668648..669988(+) (pilR) [Methylomonas sp. 2B]
MSPPVTLVVDDEPDIRELLEITLNRMDIQTRCAADLAGAKQLLANQRFDLCLTDMKLPDGDGLELVDHIQACGLPLPVAV
ITAHGNMDIAIKAMKKGAFDFLSKPVDLAVLRQLVNHALQASQGRAAEKERRTRDVLLGDSVPMRAIRSKIEKVARNQAP
VYISGESGSGKELVARLIHQQSPRGAQPFVAINCGAIPLELMESEFFGHKKGSFTGAVSDKQGLFQAAEGGTLFLDEVAD
LPLPLQVKLLRAIQEKKVRPVGEQREVPVDVRLLSATHKDLAKMVQEGAFRQDLYYRINVIELNLPPLRAREADIPQLTR
HLLTKLAAANGTAIPDLSDAAWRALKGYCFPGNVRELENILERALALHEGNLIDVDDLNLPLGLEAAAAEDFDAQKMSLE
SYLEGIEKKALSSALEENRWNKTATAKQLGLTFRSLRYRLKKLGLE

Nucleotide

• Length: 1341 bp

>NTDB_id=1066193 ACF0KO_RS02940 WP_064031613.1 668648..669988(+) (pilR) [Methylomonas sp. 2B]
ATGAGCCCACCCGTCACGCTGGTTGTCGACGACGAGCCCGACATTCGGGAATTGCTGGAAATCACGCTGAACCGAATGGA
CATTCAAACCCGCTGCGCGGCTGATTTGGCCGGGGCCAAGCAATTGCTGGCCAATCAACGTTTCGATCTGTGTTTGACCG
ATATGAAATTACCGGACGGCGACGGTTTGGAACTGGTCGACCACATCCAGGCCTGCGGTCTGCCGTTGCCGGTGGCGGTG
ATTACCGCGCACGGCAATATGGATATCGCCATCAAGGCCATGAAAAAAGGGGCTTTCGACTTCCTATCCAAGCCGGTCGA
TTTGGCGGTGTTGCGGCAGCTGGTCAACCATGCGTTGCAAGCCTCGCAAGGGCGGGCAGCCGAAAAAGAGCGCCGCACTC
GCGATGTGTTGTTGGGCGATTCGGTACCGATGCGGGCGATACGCTCGAAAATCGAGAAGGTGGCGCGCAATCAGGCGCCG
GTCTACATCAGCGGTGAGTCCGGTTCCGGCAAGGAGTTGGTGGCGCGCTTGATTCATCAGCAAAGCCCGCGCGGCGCGCA
GCCCTTTGTCGCGATCAATTGCGGCGCGATTCCGCTGGAGTTAATGGAAAGCGAGTTCTTCGGTCATAAAAAAGGCAGCT
TTACCGGCGCGGTCAGCGACAAGCAAGGCTTGTTTCAGGCTGCCGAAGGCGGCACGCTGTTTCTCGACGAAGTCGCCGAT
TTGCCGTTGCCGTTGCAAGTCAAATTGTTGCGAGCCATCCAGGAAAAGAAGGTCCGGCCGGTTGGCGAGCAACGCGAAGT
CCCGGTTGACGTGCGCTTGCTGAGTGCCACGCATAAGGACTTGGCGAAAATGGTCCAGGAAGGGGCGTTTCGGCAGGATT
TGTATTACCGGATCAATGTCATCGAACTGAATTTGCCGCCGCTGCGGGCCAGGGAAGCCGATATTCCGCAATTGACCCGC
CACTTACTGACCAAGTTAGCCGCCGCCAACGGCACGGCAATTCCCGATCTGAGCGATGCGGCTTGGCGAGCGCTAAAGGG
GTACTGCTTTCCAGGCAATGTGCGGGAATTGGAAAACATTCTCGAGCGAGCGTTGGCCTTGCACGAGGGCAATCTGATCG
ATGTTGACGATTTGAATTTGCCGTTGGGGCTGGAGGCTGCCGCGGCCGAGGATTTCGACGCGCAAAAGATGTCGCTCGAA
AGCTATTTGGAGGGCATCGAAAAGAAAGCGCTGAGCAGTGCGTTGGAAGAAAACCGCTGGAATAAAACCGCGACCGCCAA
GCAACTGGGCTTGACCTTCCGCTCGTTGCGGTATCGGCTGAAAAAGCTGGGACTGGAGTGA

Domains

Predicted by InterproScan.

• Sigma-54 interaction domain (Sigma54_activat) (138-303)

• Response regulator receiver domain (Response_reg) (7-115)

• Bacterial regulatory protein, Fis family (HTH_8) (403-443)

3D structure

• AlphaFold DB: A0A177N1L6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	63.111	100	0.637
pilR	Acinetobacter baumannii strain A118	50.866	100	0.527