Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   AABJ45_RS07830 Genome accession   NZ_AP028611
Coordinates   1539140..1540372 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain Sep6     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1540574..1551006 1539140..1540372 flank 202


Gene organization within MGE regions


Location: 1539140..1551006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABJ45_RS07830 (TKY121527_15670) clpX 1539140..1540372 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  AABJ45_RS07835 - 1540404..1540574 (-) 171 WP_000442275.1 hypothetical protein -
  AABJ45_RS07840 (TKY121527_15680) - 1540574..1541080 (-) 507 WP_000162484.1 dihydrofolate reductase -
  AABJ45_RS07845 (TKY121527_15690) - 1541210..1541728 (-) 519 WP_000229874.1 Dps family protein -
  AABJ45_RS07850 (TKY121527_15700) lytC 1542224..1543728 (-) 1505 Protein_1554 choline binding-anchored murein hydrolase LytC -
  AABJ45_RS07855 (TKY121527_15710) tpiA 1543766..1544524 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  AABJ45_RS07860 (TKY121527_15720) - 1544622..1545299 (-) 678 WP_000221613.1 DnaD domain-containing protein -
  AABJ45_RS07865 (TKY121527_15730) metA 1545308..1546252 (-) 945 WP_001122712.1 homoserine O-succinyltransferase -
  AABJ45_RS07870 (TKY121527_15750) - 1546434..1546946 (-) 513 WP_001049323.1 adenine phosphoribosyltransferase -
  AABJ45_RS07875 (TKY121527_15760) - 1547033..1547791 (-) 759 WP_001287230.1 class I SAM-dependent methyltransferase -
  AABJ45_RS07880 - 1547999..1548145 (+) 147 WP_000403100.1 hypothetical protein -
  AABJ45_RS07885 (TKY121527_15770) ugpC 1548292..1549422 (-) 1131 WP_000229961.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
  AABJ45_RS07890 (TKY121527_15790) - 1549750..1551006 (+) 1257 WP_061714154.1 ISL3-like element IS1167A family transposase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=106593 AABJ45_RS07830 WP_000106346.1 1539140..1540372(-) (clpX) [Streptococcus pneumoniae strain Sep6]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=106593 AABJ45_RS07830 WP_000106346.1 1539140..1540372(-) (clpX) [Streptococcus pneumoniae strain Sep6]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATTGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAATAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTCATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTAGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment