Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AABA19_RS01920 Genome accession   NZ_AP028609
Coordinates   366709..367398 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain Sep4     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 361709..372398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS01895 (TKY121806_03660) gpsB 361818..362147 (+) 330 WP_000146522.1 cell division regulator GpsB -
  AABA19_RS01905 (TKY121806_03670) - 362633..363790 (+) 1158 WP_000711374.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  AABA19_RS01910 (TKY121806_03680) mapZ 363803..365197 (+) 1395 WP_338171346.1 cell division site-positioning protein MapZ -
  AABA19_RS01915 (TKY121806_03690) gndA 365273..366697 (+) 1425 WP_000158768.1 NADP-dependent phosphogluconate dehydrogenase -
  AABA19_RS01920 (TKY121806_03700) covR 366709..367398 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  AABA19_RS01925 (TKY121806_03710) cbpJ 367497..368495 (+) 999 WP_000771053.1 choline-binding protein CbpJ -
  AABA19_RS01930 - 368613..369845 (-) 1233 WP_000765684.1 MFS transporter -
  AABA19_RS01935 (TKY121806_03740) - 370004..370474 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  AABA19_RS01940 - 370374..370732 (-) 359 Protein_379 lantibiotic-modifying protein -
  AABA19_RS10880 - 371395..371562 (+) 168 Protein_380 transposase -
  AABA19_RS10885 - 371602..371724 (+) 123 Protein_381 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=106413 AABA19_RS01920 WP_000518008.1 366709..367398(+) (covR) [Streptococcus pneumoniae strain Sep4]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=106413 AABA19_RS01920 WP_000518008.1 366709..367398(+) (covR) [Streptococcus pneumoniae strain Sep4]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment