Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ACG3JK_RS04665 Genome accession   NZ_CP171738
Coordinates   957541..958902 (-) Length   453 a.a.
NCBI ID   WP_004234616.1    Uniprot ID   A0A0E2U9A9
Organism   Streptococcus parauberis strain DB-M23     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 952541..963902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JK_RS04655 (ACG3JK_04655) rnc 955937..956629 (-) 693 WP_003103277.1 ribonuclease III -
  ACG3JK_RS04660 (ACG3JK_04660) vicX 956727..957536 (-) 810 WP_037619792.1 MBL fold metallo-hydrolase Regulator
  ACG3JK_RS04665 (ACG3JK_04665) vicK 957541..958902 (-) 1362 WP_004234616.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACG3JK_RS04670 (ACG3JK_04670) vicR 958895..959605 (-) 711 WP_013793732.1 response regulator YycF Regulator
  ACG3JK_RS04675 (ACG3JK_04675) - 959853..960632 (+) 780 WP_003106355.1 amino acid ABC transporter ATP-binding protein -
  ACG3JK_RS04680 (ACG3JK_04680) - 960645..961460 (+) 816 WP_013793731.1 transporter substrate-binding domain-containing protein -
  ACG3JK_RS04685 (ACG3JK_04685) - 961474..962178 (+) 705 WP_003104614.1 amino acid ABC transporter permease -
  ACG3JK_RS04690 (ACG3JK_04690) - 962193..962840 (+) 648 WP_003104005.1 amino acid ABC transporter permease -
  ACG3JK_RS04695 (ACG3JK_04695) - 962863..963870 (-) 1008 WP_003106351.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 51935.33 Da        Isoelectric Point: 4.9370

>NTDB_id=1064066 ACG3JK_RS04665 WP_004234616.1 957541..958902(-) (vicK) [Streptococcus parauberis strain DB-M23]
MTNNIIGNLSLFEISILLLLIFVAIYFVHLAVRDYRNAKIIKQMSQKIRDLINGRYTDDINLRADMELMDLSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATDRSGQILMINETAQNQLNMTKEQALKKNITDLLDADEPYTYRELVSKTPI
VTISRRDETGEFNSLRLRFALNRRESGFISGLVVVIHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMITDLLNLSRIDNQATRLTVEMTNFTAFMTSILNRFDLVKNQNTISGKSYEIIRDYPINS
IWVEIDNDKMTQVVENILNNAIKYSPDGGKITVKMKTTDNQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHQGFIWAKSEYSKGSTFTIVLPYDKEAVMYDDVDEWEDEID

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=1064066 ACG3JK_RS04665 WP_004234616.1 957541..958902(-) (vicK) [Streptococcus parauberis strain DB-M23]
ATGACTAATAATATTATAGGAAATTTATCCTTATTTGAAATATCGATTCTCTTACTTTTGATTTTTGTTGCCATTTACTT
TGTACATTTGGCAGTTCGTGATTATCGTAATGCAAAAATCATTAAACAGATGAGTCAAAAAATTAGAGACTTAATCAATG
GACGCTATACAGACGATATTAACTTGCGTGCTGATATGGAATTAATGGATTTATCTGAGCAATTAAATGATTTATCAGAT
GTTTTTCGGTTAACCCATGAGAATTTGGCCCAAGAAAAAAATCGTTTAGCGTCGATTTTGGCTTATATGACCGATGGAGT
CTTAGCGACCGACCGTTCTGGTCAGATTTTGATGATCAATGAAACGGCTCAAAATCAGCTTAACATGACCAAAGAGCAAG
CACTTAAAAAGAATATTACGGATTTGTTAGATGCTGATGAACCCTATACATATCGGGAGTTAGTTTCTAAAACACCAATT
GTTACAATTAGTCGGCGTGATGAAACTGGAGAATTTAATTCGTTAAGGTTACGTTTTGCTTTGAATAGAAGAGAGAGTGG
CTTTATTTCTGGTTTAGTTGTTGTAATCCATGATACAACAGAGCAAGAAAAAGAAGAACGTGAACGACGCTTATTTGTTT
CTAACGTAAGTCATGAATTGCGGACACCGCTCACGTCTGTAAAATCTTATTTGGAAGCATTGGATGAAGGTGCCATAAAA
GAAGATATTGCTCCAAGTTTCATCAAGGTTTCATTAGATGAAACAAACCGGATGATGCGAATGATAACTGATCTCTTGAA
CTTATCAAGAATTGATAATCAGGCGACTCGTTTGACGGTTGAGATGACCAATTTCACTGCCTTTATGACTTCTATCTTGA
ATCGTTTTGATTTGGTCAAAAACCAAAATACCATTTCAGGTAAAAGTTATGAGATTATTCGAGATTATCCAATTAACTCA
ATTTGGGTTGAAATTGATAATGATAAGATGACTCAAGTCGTTGAAAACATTTTGAATAATGCTATTAAATATTCACCTGA
TGGTGGTAAAATTACAGTTAAAATGAAAACAACTGATAATCAGCTCATTATTTCCATTTCTGATCAAGGATTGGGTATTC
CGAAAAAAGATTTACCTCTTATTTTTGACCGCTTTTATCGGGTGGATAAAGCAAGAAGTCGTGCGCAAGGTGGGACTGGT
CTGGGCTTAGCAATTGCAAAAGAGATAATTAAACAGCATCAAGGCTTTATTTGGGCTAAAAGTGAGTATAGTAAAGGTTC
AACTTTTACAATAGTCTTACCATATGATAAAGAAGCTGTTATGTATGATGATGTTGATGAATGGGAGGACGAAATCGACT
AA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

PAS fold (PAS)

(95-171)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2U9A9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

72.222

91.391

0.66
  micB Streptococcus pneumoniae Cp1015

67.681

94.26

0.638

Multiple sequence alignment