Detailed information    

insolico Bioinformatically predicted

Overview

Name   luxO   Type   Regulator
Locus tag   ACG4IT_RS09235 Genome accession   NZ_CP171686
Coordinates   2026969..2028336 (-) Length   455 a.a.
NCBI ID   WP_394856927.1    Uniprot ID   -
Organism   Vibrio cholerae strain M686     
Function   promote HapR production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2021969..2033336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG4IT_RS09200 moaE 2022692..2023144 (-) 453 WP_000350081.1 molybdopterin synthase catalytic subunit MoaE -
  ACG4IT_RS09205 moaD 2023146..2023391 (-) 246 WP_000598590.1 molybdopterin synthase sulfur carrier subunit -
  ACG4IT_RS09210 moaC 2023388..2023867 (-) 480 WP_000080915.1 cyclic pyranopterin monophosphate synthase MoaC -
  ACG4IT_RS09215 moaB 2023878..2024390 (-) 513 WP_000509705.1 molybdenum cofactor biosynthesis protein B -
  ACG4IT_RS09220 moaA 2024450..2025439 (-) 990 WP_000068572.1 GTP 3',8-cyclase MoaA -
  ACG4IT_RS09225 - 2025745..2026635 (+) 891 WP_000061070.1 YvcK family protein -
  ACG4IT_RS09230 luxU 2026624..2026965 (-) 342 WP_001209531.1 quorum-sensing phosphorelay protein LuxU -
  ACG4IT_RS09235 luxO 2026969..2028336 (-) 1368 WP_394856927.1 quorum-sensing sigma-54 dependent transcriptional regulator LuxO Regulator
  ACG4IT_RS09240 uvrB 2028767..2030797 (-) 2031 WP_000029983.1 excinuclease ABC subunit UvrB -
  ACG4IT_RS09250 rsxA 2031679..2032260 (+) 582 WP_000141550.1 electron transport complex subunit RsxA -
  ACG4IT_RS09255 rsxB 2032260..2032847 (+) 588 WP_000104488.1 electron transport complex subunit RsxB -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50793.03 Da        Isoelectric Point: 5.5757

>NTDB_id=1063258 ACG4IT_RS09235 WP_394856927.1 2026969..2028336(-) (luxO) [Vibrio cholerae strain M686]
MVEDTASVAALYRSYLTPLDIDINIVGTGRDAIESIGRREPDLILLDLRLPDMTGMDVLYAVKEKSPDVPIVFMTAHGSI
DTAVEAMRHGAQDFLIKPCEADRLRVTVNNAIRKASKLKNDVDNKNQNYQGFIGSSQTMQAVYRTIDSAASSKASIFITG
ESGTGKEVGAEAIHAASKRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATERQGAAEAADGGTLFLDELCEMDLDL
QTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRARGDDVIEIAYSLLGF
MSKEEGKDFVRLSAEVVERFRQYEWPGNVRQLQNVLRNVVVLNEGREITLDMLPPPLNQMSAPINRALPLAHENKVSVHE
IFPLWMTEKQAIEQAIEACDGNIPRAATYLDVSPSTIYRKLQTWNEKVKEKEKER

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1063258 ACG4IT_RS09235 WP_394856927.1 2026969..2028336(-) (luxO) [Vibrio cholerae strain M686]
ATGGTAGAAGACACGGCGTCGGTGGCGGCGCTGTATCGTTCTTACCTCACACCGCTGGATATTGATATCAATATCGTGGG
TACCGGACGCGATGCCATCGAGAGTATTGGCCGTCGCGAGCCTGACTTAATCCTGCTGGATTTACGTTTGCCAGATATGA
CGGGGATGGACGTACTCTATGCAGTGAAAGAGAAATCACCGGATGTGCCTATCGTGTTTATGACCGCTCATGGTTCGATT
GATACGGCGGTTGAAGCCATGCGTCATGGTGCGCAAGACTTTTTGATCAAGCCGTGTGAAGCGGACCGACTGCGGGTCAC
AGTGAATAATGCGATTCGCAAAGCCTCGAAACTCAAAAACGATGTTGATAATAAAAATCAAAACTATCAAGGCTTTATTG
GTAGCAGTCAAACCATGCAGGCGGTGTACCGCACCATTGACTCTGCGGCGAGCAGCAAAGCCAGTATTTTTATTACCGGC
GAAAGTGGTACAGGTAAAGAAGTGGGCGCGGAAGCGATTCATGCCGCGAGCAAGCGTGGAGATAAGCCATTTATCGCCAT
CAACTGTGCGGCCATTCCGAAAGATCTGATTGAAAGTGAGTTGTTTGGTCACGTCAAAGGGGCTTTTACTGGGGCGGCGA
CTGAGCGTCAAGGCGCGGCAGAAGCGGCTGATGGGGGAACCCTCTTTTTGGATGAATTGTGCGAAATGGATCTGGATCTG
CAGACCAAACTTCTGCGCTTTATTCAGACAGGGACATTCCAAAAAGTCGGCTCTTCCAAAATGAAAAGCGTGGATGTGCG
TTTTGTGTGTGCAACGAACCGCGATCCGTGGAAGGAAGTGCAAGAAGGACGCTTTCGTGAAGACCTGTACTACCGCTTGT
ATGTGATCCCGCTGCATTTACCGCCATTGCGCGCGCGTGGTGATGATGTGATCGAGATTGCTTATTCACTGCTTGGCTTT
ATGTCCAAGGAAGAGGGCAAAGATTTTGTCCGTTTGTCGGCTGAAGTGGTGGAGCGTTTTCGCCAATACGAGTGGCCGGG
CAACGTGCGTCAATTGCAAAACGTTTTGCGCAACGTGGTTGTGCTCAATGAAGGTCGTGAAATCACCCTAGATATGCTGC
CTCCTCCTCTTAATCAAATGTCCGCGCCGATCAATCGGGCTTTACCGCTTGCGCATGAGAATAAAGTATCCGTGCATGAG
ATTTTTCCGCTGTGGATGACCGAAAAACAAGCCATTGAACAAGCCATCGAAGCGTGTGATGGCAACATTCCCCGTGCCGC
AACCTATCTGGATGTCAGCCCGTCAACCATCTATCGCAAGCTGCAAACTTGGAATGAAAAAGTGAAAGAAAAAGAGAAGG
AACGGTAA

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(404-442)

Response regulator receiver domain (Response_reg)

(2-108)

Sigma-54 interaction domain (Sigma54_activat)

(133-298)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  luxO Vibrio cholerae strain A1552

99.78

100

0.998
  pilR Pseudomonas aeruginosa PAK

38.274

99.341

0.38

Multiple sequence alignment