Detailed information NTG0106304

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: AABA14_RS09650
• Genome accession: NZ_AP028607
• Coordinates: 1859140..1860177 (-)
• Length: 345 a.a.
• NCBI ID: WP_338168409.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep2
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1854140..1865177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA14_RS09625 (TKY123642_18930)	-	1854879..1856210 (-)	1332	WP_016398203.1	hemolysin family protein	-
AABA14_RS09630 (TKY123642_18940)	endA	1856501..1857325 (-)	825	WP_001036784.1	DNA-entry nuclease EndA	Machinery gene
AABA14_RS09635 (TKY123642_18950)	-	1857364..1857552 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
AABA14_RS09640 (TKY123642_18960)	murA	1857545..1858828 (-)	1284	WP_061762444.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
AABA14_RS09645 (TKY123642_18970)	-	1858852..1859082 (-)	231	WP_000250393.1	DUF1146 family protein	-
AABA14_RS09650 (TKY123642_18980)	sepM	1859140..1860177 (-)	1038	WP_338168409.1	SepM family pheromone-processing serine protease	Regulator
AABA14_RS09655 (TKY123642_18990)	coaD	1860161..1860649 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
AABA14_RS09660 (TKY123642_19000)	rsmD	1860639..1861178 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
AABA14_RS09665 (TKY123642_19010)	asnA	1861243..1862235 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
AABA14_RS09670 (TKY123642_19020)	-	1862347..1863030 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
AABA14_RS09675 (TKY123642_19030)	-	1863086..1863826 (-)	741	WP_000152679.1	RNA methyltransferase	-
AABA14_RS09680 (TKY123642_19040)	-	1863860..1864138 (+)	279	WP_001174613.1	acylphosphatase	-
AABA14_RS09685 (TKY123642_19050)	yidC	1864216..1865142 (+)	927	WP_000835949.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37523.55 Da
• Isoelectric Point: 5.0677

>NTDB_id=106304 AABA14_RS09650 WP_338168409.1 1859140..1860177(-) (sepM) [Streptococcus pneumoniae strain Sep2]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSADGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=106304 AABA14_RS09650 WP_338168409.1 1859140..1860177(-) (sepM) [Streptococcus pneumoniae strain Sep2]
ATGAAAAAAAAGATTAGATGGCCCTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTATTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGACGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

• PDZ domain (PDZ_2) (130-193)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591