Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AABA14_RS09630 Genome accession   NZ_AP028607
Coordinates   1856501..1857325 (-) Length   274 a.a.
NCBI ID   WP_001036784.1    Uniprot ID   A0A0E7E4I0
Organism   Streptococcus pneumoniae strain Sep2     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1851501..1862325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA14_RS09625 (TKY123642_18930) - 1854879..1856210 (-) 1332 WP_016398203.1 hemolysin family protein -
  AABA14_RS09630 (TKY123642_18940) endA 1856501..1857325 (-) 825 WP_001036784.1 DNA-entry nuclease EndA Machinery gene
  AABA14_RS09635 (TKY123642_18950) - 1857364..1857552 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  AABA14_RS09640 (TKY123642_18960) murA 1857545..1858828 (-) 1284 WP_061762444.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AABA14_RS09645 (TKY123642_18970) - 1858852..1859082 (-) 231 WP_000250393.1 DUF1146 family protein -
  AABA14_RS09650 (TKY123642_18980) sepM 1859140..1860177 (-) 1038 WP_338168409.1 SepM family pheromone-processing serine protease Regulator
  AABA14_RS09655 (TKY123642_18990) coaD 1860161..1860649 (-) 489 WP_001280746.1 pantetheine-phosphate adenylyltransferase -
  AABA14_RS09660 (TKY123642_19000) rsmD 1860639..1861178 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AABA14_RS09665 (TKY123642_19010) asnA 1861243..1862235 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29931.63 Da        Isoelectric Point: 10.1197

>NTDB_id=106303 AABA14_RS09630 WP_001036784.1 1856501..1857325(-) (endA) [Streptococcus pneumoniae strain Sep2]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=106303 AABA14_RS09630 WP_001036784.1 1856501..1857325(-) (endA) [Streptococcus pneumoniae strain Sep2]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E7E4I0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.27

100

0.993
  endA Streptococcus pneumoniae D39

99.27

100

0.993
  endA Streptococcus pneumoniae R6

99.27

100

0.993
  endA Streptococcus pneumoniae TIGR4

99.27

100

0.993

Multiple sequence alignment