Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AABA14_RS01985 Genome accession   NZ_AP028607
Coordinates   371427..372116 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 366427..377116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA14_RS01960 (TKY123642_03760) gpsB 366560..366889 (+) 330 WP_000146522.1 cell division regulator GpsB -
  AABA14_RS01970 (TKY123642_03770) - 367375..368532 (+) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  AABA14_RS01975 (TKY123642_03780) mapZ 368545..369915 (+) 1371 WP_016398385.1 mid-cell-anchored protein MapZ -
  AABA14_RS01980 (TKY123642_03790) gndA 369991..371415 (+) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  AABA14_RS01985 (TKY123642_03800) covR 371427..372116 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  AABA14_RS01990 (TKY123642_03810) cbpJ 372215..373213 (+) 999 WP_000771053.1 choline-binding protein CbpJ -
  AABA14_RS01995 (TKY123642_03820) - 373331..374563 (-) 1233 WP_016399630.1 MFS transporter -
  AABA14_RS02000 (TKY123642_03830) - 374606..375193 (-) 588 WP_025173699.1 lanthionine synthetase LanC family protein -
  AABA14_RS02005 - 375093..375482 (-) 390 WP_253188961.1 lanthionine synthetase LanC family protein -
  AABA14_RS02010 - 376077..376406 (+) 330 WP_016398382.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=106259 AABA14_RS01985 WP_000518011.1 371427..372116(+) (covR) [Streptococcus pneumoniae strain Sep2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=106259 AABA14_RS01985 WP_000518011.1 371427..372116(+) (covR) [Streptococcus pneumoniae strain Sep2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment