Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   AAA996_RS07350 Genome accession   NZ_AP028606
Coordinates   1448404..1449636 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain Sep1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1443404..1454636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA996_RS07320 (TKY121773_14500) - 1443594..1444559 (+) 966 WP_000081011.1 NAD(P)/FAD-dependent oxidoreductase -
  AAA996_RS07325 (TKY121773_14510) whiA 1444593..1445504 (-) 912 WP_000011306.1 DNA-binding protein WhiA -
  AAA996_RS07330 (TKY121773_14520) - 1445501..1446478 (-) 978 WP_001231086.1 YvcK family protein -
  AAA996_RS07335 (TKY121773_14530) rapZ 1446475..1447365 (-) 891 WP_000163033.1 RNase adapter RapZ -
  AAA996_RS07340 (TKY121773_14540) - 1447417..1447797 (-) 381 WP_001140412.1 RidA family protein -
  AAA996_RS07345 (TKY121773_14550) yihA 1447808..1448395 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  AAA996_RS07350 (TKY121773_14560) clpX 1448404..1449636 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  AAA996_RS07355 - 1449668..1449838 (-) 171 WP_000442275.1 hypothetical protein -
  AAA996_RS07360 (TKY121773_14570) - 1449838..1450344 (-) 507 WP_000162484.1 dihydrofolate reductase -
  AAA996_RS07365 (TKY121773_14580) - 1450474..1450992 (-) 519 WP_000229874.1 Dps family protein -
  AAA996_RS07370 (TKY121773_14590) - 1451542..1452603 (+) 1062 Protein_1458 ISL3-like element IS1167A family transposase -
  AAA996_RS07375 (TKY121773_14600) - 1452768..1454114 (+) 1347 WP_001842410.1 IS1380-like element ISSpn5 family transposase -
  AAA996_RS07380 - 1454306..1454529 (+) 224 Protein_1460 transposase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=106204 AAA996_RS07350 WP_000106346.1 1448404..1449636(-) (clpX) [Streptococcus pneumoniae strain Sep1]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=106204 AAA996_RS07350 WP_000106346.1 1448404..1449636(-) (clpX) [Streptococcus pneumoniae strain Sep1]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment