Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACF8MK_RS08925 Genome accession   NZ_CP171154
Coordinates   2069988..2070647 (+) Length   219 a.a.
NCBI ID   WP_058510655.1    Uniprot ID   A0A0W0ZHN3
Organism   Legionella sp. 227     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2064988..2075647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF8MK_RS08895 (ACF8MK_08895) - 2065195..2065860 (-) 666 WP_265703445.1 50S ribosomal protein L25/general stress protein Ctc -
  ACF8MK_RS08900 (ACF8MK_08900) rplU 2066062..2066373 (+) 312 WP_265703446.1 50S ribosomal protein L21 -
  ACF8MK_RS08905 (ACF8MK_08905) rpmA 2066386..2066664 (+) 279 WP_028381048.1 50S ribosomal protein L27 -
  ACF8MK_RS08910 (ACF8MK_08910) cgtA 2066828..2067853 (+) 1026 WP_265703447.1 Obg family GTPase CgtA -
  ACF8MK_RS08915 (ACF8MK_08915) - 2067809..2068906 (-) 1098 WP_392536352.1 competence/damage-inducible protein A -
  ACF8MK_RS08920 (ACF8MK_08920) phhA 2069082..2069900 (+) 819 WP_392536353.1 phenylalanine 4-monooxygenase -
  ACF8MK_RS08925 (ACF8MK_08925) letA 2069988..2070647 (+) 660 WP_058510655.1 two-component system response regulator LetA Regulator
  ACF8MK_RS08930 (ACF8MK_08930) uvrC 2070785..2072641 (+) 1857 WP_392536354.1 excinuclease ABC subunit UvrC -
  ACF8MK_RS08935 (ACF8MK_08935) - 2072838..2073551 (+) 714 WP_265703451.1 L,D-transpeptidase -
  ACF8MK_RS08940 (ACF8MK_08940) - 2073560..2074123 (+) 564 WP_265703477.1 endopeptidase IV -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24361.38 Da        Isoelectric Point: 5.1789

>NTDB_id=1060335 ACF8MK_RS08925 WP_058510655.1 2069988..2070647(+) (letA) [Legionella sp. 227]
MIKVLIVDDHALVRMGIRRLLEDMSDVEVVADAESGEQALALVKKHSPDVVLLDMKMPGIDGWEVTRRLKKSNPHVKVIA
VTAMCSDVLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGERYLSAEIAQKMAINSLEEVQGSPFDVLSEREMQVMLMI
TSGMNVQEISDRLFLSTKTINGYRYRTFEKLGIKNDVELTYLALKHGIIENPIDLASED

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1060335 ACF8MK_RS08925 WP_058510655.1 2069988..2070647(+) (letA) [Legionella sp. 227]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTCGAATGGGGATTCGACGATTACTCGAAGATATGTCGGATGT
AGAGGTAGTTGCTGATGCAGAAAGTGGTGAGCAAGCTTTGGCATTAGTAAAAAAACATTCCCCCGACGTGGTCCTTTTAG
ATATGAAAATGCCTGGAATTGATGGCTGGGAAGTAACGCGTCGTCTAAAAAAATCAAATCCGCACGTTAAGGTTATTGCT
GTAACTGCAATGTGTTCTGATGTGTTGCCTACTCGAGTATTACAATTAGGTGCCATGGGCTATCTGACGAAAGAATCAGG
TGCTGAAGAAATGGCGGCTGCGATACGTAAAGTTGCTAAAGGCGAGAGATATTTAAGTGCTGAGATTGCTCAGAAAATGG
CGATCAATAGCTTGGAAGAAGTACAAGGCTCACCTTTCGATGTGTTATCTGAACGCGAAATGCAAGTCATGTTGATGATT
ACTAGTGGTATGAATGTTCAGGAAATAAGTGACCGGCTATTCCTTAGTACCAAAACGATTAATGGGTATCGTTACCGTAC
ATTTGAAAAATTAGGTATTAAAAATGATGTAGAGCTTACTTATTTGGCTCTAAAGCATGGAATTATAGAAAATCCCATCG
ATCTGGCGTCAGAAGATTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-203)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0W0ZHN3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

89.041

100

0.89
  letA Legionella pneumophila strain ERS1305867

89.041

100

0.89

Multiple sequence alignment