Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | AAA985_RS07865 | Genome accession | NZ_AP028603 |
| Coordinates | 1510801..1512033 (-) | Length | 410 a.a. |
| NCBI ID | WP_000106346.1 | Uniprot ID | A0A064C077 |
| Organism | Streptococcus pneumoniae strain Pne2 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1465734..1520031 | 1510801..1512033 | within | 0 |
Gene organization within MGE regions
Location: 1465734..1520031
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AAA985_RS07545 (TKY181970_14990) | - | 1465734..1466702 (-) | 969 | WP_338168205.1 | N-acetylmuramoyl-L-alanine amidase family protein | - |
| AAA985_RS07550 (TKY181970_15000) | - | 1466706..1467038 (-) | 333 | WP_001186242.1 | phage holin | - |
| AAA985_RS07555 (TKY181970_15010) | - | 1467042..1467458 (-) | 417 | WP_050211460.1 | phage holin family protein | - |
| AAA985_RS07560 (TKY181970_15020) | - | 1467468..1467818 (-) | 351 | WP_000852249.1 | hypothetical protein | - |
| AAA985_RS07565 (TKY181970_15030) | - | 1467821..1468024 (-) | 204 | WP_001091109.1 | hypothetical protein | - |
| AAA985_RS07570 | - | 1468005..1468121 (-) | 117 | WP_001063632.1 | hypothetical protein | - |
| AAA985_RS07575 (TKY181970_15040) | - | 1468118..1474561 (-) | 6444 | WP_338168206.1 | tail fiber domain-containing protein | - |
| AAA985_RS07580 (TKY181970_15050) | - | 1474566..1474916 (-) | 351 | WP_000068032.1 | DUF6711 family protein | - |
| AAA985_RS07585 (TKY181970_15060) | - | 1474925..1478578 (-) | 3654 | WP_000212167.1 | hypothetical protein | - |
| AAA985_RS07590 (TKY181970_15070) | - | 1478565..1478915 (-) | 351 | WP_000478011.1 | hypothetical protein | - |
| AAA985_RS07595 (TKY181970_15080) | - | 1478954..1479334 (-) | 381 | WP_001185636.1 | DUF6096 family protein | - |
| AAA985_RS07600 (TKY181970_15090) | - | 1479339..1479752 (-) | 414 | WP_000880674.1 | phage tail tube protein | - |
| AAA985_RS07605 (TKY181970_15100) | - | 1479755..1480123 (-) | 369 | WP_000608235.1 | hypothetical protein | - |
| AAA985_RS07610 (TKY181970_15110) | - | 1480120..1480635 (-) | 516 | WP_001292567.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| AAA985_RS07615 (TKY181970_15120) | - | 1480610..1480948 (-) | 339 | WP_000478942.1 | hypothetical protein | - |
| AAA985_RS07620 (TKY181970_15130) | - | 1480929..1481240 (-) | 312 | WP_000021221.1 | phage head-tail connector protein | - |
| AAA985_RS07625 (TKY181970_15140) | - | 1481242..1481430 (-) | 189 | WP_000669352.1 | hypothetical protein | - |
| AAA985_RS07630 (TKY181970_15150) | - | 1481420..1481602 (-) | 183 | WP_000054936.1 | Rho termination factor N-terminal domain-containing protein | - |
| AAA985_RS07635 (TKY181970_15160) | - | 1481607..1482452 (-) | 846 | WP_000123893.1 | N4-gp56 family major capsid protein | - |
| AAA985_RS07640 (TKY181970_15170) | - | 1482458..1483027 (-) | 570 | WP_001001557.1 | DUF4355 domain-containing protein | - |
| AAA985_RS07645 (TKY181970_15180) | - | 1483230..1483481 (-) | 252 | WP_000913247.1 | DUF6275 family protein | - |
| AAA985_RS07650 (TKY181970_15190) | - | 1483483..1483728 (-) | 246 | WP_000877357.1 | hypothetical protein | - |
| AAA985_RS07655 (TKY181970_15200) | - | 1483771..1484184 (-) | 414 | WP_000565276.1 | HD domain-containing protein | - |
| AAA985_RS07660 (TKY181970_15210) | - | 1484181..1484390 (-) | 210 | WP_000651747.1 | hypothetical protein | - |
| AAA985_RS07665 (TKY181970_15220) | - | 1484392..1486029 (-) | 1638 | WP_179855908.1 | minor capsid protein | - |
| AAA985_RS07670 (TKY181970_15230) | - | 1485938..1487407 (-) | 1470 | WP_000285396.1 | phage portal protein | - |
| AAA985_RS07675 (TKY181970_15240) | - | 1487419..1488717 (-) | 1299 | WP_000084430.1 | PBSX family phage terminase large subunit | - |
| AAA985_RS07680 (TKY181970_15250) | - | 1488695..1489195 (-) | 501 | WP_012677066.1 | terminase small subunit | - |
| AAA985_RS07690 (TKY181970_15260) | - | 1489587..1489991 (-) | 405 | WP_001030243.1 | DUF1492 domain-containing protein | - |
| AAA985_RS07695 (TKY181970_15270) | - | 1490062..1490433 (-) | 372 | WP_001247152.1 | hypothetical protein | - |
| AAA985_RS07700 (TKY181970_15280) | - | 1490430..1490642 (-) | 213 | WP_000160160.1 | hypothetical protein | - |
| AAA985_RS07705 (TKY181970_15290) | - | 1490643..1491143 (-) | 501 | WP_001021770.1 | DUF1642 domain-containing protein | - |
| AAA985_RS07710 (TKY181970_15300) | - | 1491145..1491459 (-) | 315 | WP_000391841.1 | hypothetical protein | - |
| AAA985_RS07715 (TKY181970_15310) | - | 1491610..1491948 (-) | 339 | WP_000119452.1 | hypothetical protein | - |
| AAA985_RS07720 (TKY181970_15320) | - | 1491948..1492100 (-) | 153 | WP_000122746.1 | hypothetical protein | - |
| AAA985_RS07725 (TKY181970_15330) | - | 1492394..1493737 (-) | 1344 | WP_000580027.1 | virulence-associated E family protein | - |
| AAA985_RS07730 (TKY181970_15340) | - | 1493740..1494561 (-) | 822 | WP_001838318.1 | bifunctional DNA primase/polymerase | - |
| AAA985_RS07735 (TKY181970_15350) | - | 1494734..1495237 (-) | 504 | WP_000054338.1 | hypothetical protein | - |
| AAA985_RS07740 (TKY181970_15360) | - | 1495257..1496033 (-) | 777 | WP_000885998.1 | AAA family ATPase | - |
| AAA985_RS07745 (TKY181970_15370) | - | 1496033..1496350 (-) | 318 | WP_001044592.1 | hypothetical protein | - |
| AAA985_RS07750 (TKY181970_15380) | - | 1496369..1497562 (-) | 1194 | WP_000028860.1 | DEAD/DEAH box helicase family protein | - |
| AAA985_RS07755 (TKY181970_15390) | - | 1497525..1498010 (-) | 486 | WP_000696056.1 | hypothetical protein | - |
| AAA985_RS07760 (TKY181970_15400) | - | 1498010..1498369 (-) | 360 | WP_000422309.1 | hypothetical protein | - |
| AAA985_RS07765 (TKY181970_15410) | - | 1498369..1498851 (-) | 483 | WP_000157807.1 | siphovirus Gp157 family protein | - |
| AAA985_RS07770 (TKY181970_15420) | - | 1498844..1499566 (-) | 723 | WP_000544343.1 | HNH endonuclease signature motif containing protein | - |
| AAA985_RS07775 (TKY181970_15430) | - | 1499580..1499810 (-) | 231 | WP_000252080.1 | hypothetical protein | - |
| AAA985_RS07780 (TKY181970_15440) | - | 1499811..1500152 (-) | 342 | WP_000189405.1 | hypothetical protein | - |
| AAA985_RS07785 (TKY181970_15450) | - | 1500164..1500355 (-) | 192 | WP_000970850.1 | hypothetical protein | - |
| AAA985_RS07790 (TKY181970_15460) | - | 1500352..1500546 (-) | 195 | WP_001050924.1 | hypothetical protein | - |
| AAA985_RS07795 (TKY181970_15470) | - | 1500543..1500815 (-) | 273 | WP_000450967.1 | hypothetical protein | - |
| AAA985_RS07800 (TKY181970_15480) | - | 1500958..1501161 (+) | 204 | WP_128969726.1 | hypothetical protein | - |
| AAA985_RS07805 (TKY181970_15500) | - | 1501626..1501820 (-) | 195 | WP_029680340.1 | helix-turn-helix transcriptional regulator | - |
| AAA985_RS07810 (TKY181970_15510) | - | 1501854..1502039 (-) | 186 | WP_023396929.1 | helix-turn-helix transcriptional regulator | - |
| AAA985_RS07815 (TKY181970_15520) | - | 1502187..1502378 (+) | 192 | WP_000834623.1 | hypothetical protein | - |
| AAA985_RS07820 (TKY181970_15540) | - | 1502595..1503284 (+) | 690 | WP_000577241.1 | DUF4145 domain-containing protein | - |
| AAA985_RS07825 (TKY181970_15550) | - | 1503546..1504313 (+) | 768 | WP_001859593.1 | S24 family peptidase | - |
| AAA985_RS07830 (TKY181970_15560) | - | 1504335..1505405 (+) | 1071 | WP_000420652.1 | hypothetical protein | - |
| AAA985_RS07835 (TKY181970_15570) | - | 1505775..1506902 (+) | 1128 | WP_000266845.1 | site-specific integrase | - |
| AAA985_RS07840 (TKY181970_15580) | whiA | 1506990..1507901 (-) | 912 | WP_000011306.1 | DNA-binding protein WhiA | - |
| AAA985_RS07845 (TKY181970_15590) | - | 1507898..1508875 (-) | 978 | WP_001231086.1 | YvcK family protein | - |
| AAA985_RS07850 (TKY181970_15600) | rapZ | 1508872..1509762 (-) | 891 | WP_000163033.1 | RNase adapter RapZ | - |
| AAA985_RS07855 (TKY181970_15610) | - | 1509814..1510194 (-) | 381 | WP_001140412.1 | RidA family protein | - |
| AAA985_RS07860 (TKY181970_15620) | yihA | 1510205..1510792 (-) | 588 | WP_000422599.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| AAA985_RS07865 (TKY181970_15630) | clpX | 1510801..1512033 (-) | 1233 | WP_000106346.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| AAA985_RS07870 | - | 1512065..1512235 (-) | 171 | WP_000442275.1 | hypothetical protein | - |
| AAA985_RS07875 (TKY181970_15640) | - | 1512235..1512741 (-) | 507 | WP_000162484.1 | dihydrofolate reductase | - |
| AAA985_RS07880 (TKY181970_15650) | - | 1512871..1513389 (-) | 519 | WP_000229874.1 | Dps family protein | - |
| AAA985_RS07885 (TKY181970_15660) | - | 1513963..1515219 (+) | 1257 | WP_000436627.1 | ISL3 family transposase | - |
| AAA985_RS07890 (TKY181970_15670) | lytC | 1515308..1516813 (-) | 1506 | WP_075575672.1 | choline binding-anchored murein hydrolase LytC | - |
| AAA985_RS07895 (TKY181970_15680) | tpiA | 1516851..1517609 (-) | 759 | WP_000087897.1 | triose-phosphate isomerase | - |
| AAA985_RS07900 (TKY181970_15690) | - | 1517707..1518384 (-) | 678 | WP_000221611.1 | DnaD domain-containing protein | - |
| AAA985_RS07905 (TKY181970_15700) | metA | 1518393..1519337 (-) | 945 | WP_001122712.1 | homoserine O-succinyltransferase | - |
| AAA985_RS07910 (TKY181970_15710) | - | 1519519..1520031 (-) | 513 | WP_001049323.1 | adenine phosphoribosyltransferase | - |
Sequence
Protein
Download Length: 410 a.a. Molecular weight: 45798.35 Da Isoelectric Point: 4.4550
>NTDB_id=105971 AAA985_RS07865 WP_000106346.1 1510801..1512033(-) (clpX) [Streptococcus pneumoniae strain Pne2]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
Nucleotide
Download Length: 1233 bp
>NTDB_id=105971 AAA985_RS07865 WP_000106346.1 1510801..1512033(-) (clpX) [Streptococcus pneumoniae strain Pne2]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
86.585 |
100 |
0.866 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
57.214 |
98.049 |
0.561 |