Detailed information
Bioinformatically predicted
Overview
| Name | pptA | Type | Regulator |
| Locus tag | AAA985_RS02870 | Genome accession | NZ_AP028603 |
| Coordinates | 536133..536864 (+) | Length | 243 a.a. |
| NCBI ID | WP_000889919.1 | Uniprot ID | A0A062WNF5 |
| Organism | Streptococcus pneumoniae strain Pne2 | ||
| Function | export ComS (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 519869..548307 | 536133..536864 | within | 0 |
Gene organization within MGE regions
Location: 519869..548307
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AAA985_RS02800 (TKY181970_05470) | - | 519869..521149 (+) | 1281 | WP_001220758.1 | restriction endonuclease subunit S | - |
| AAA985_RS02805 (TKY181970_05480) | psrA | 521206..522003 (+) | 798 | WP_000651177.1 | tyrosine-type DNA invertase PsrA | - |
| AAA985_RS02810 (TKY181970_05490) | - | 522014..522619 (+) | 606 | WP_001813510.1 | restriction endonuclease subunit S | - |
| AAA985_RS02815 | - | 522567..524162 (-) | 1596 | Protein_554 | restriction endonuclease subunit S | - |
| AAA985_RS02820 (TKY181970_05520) | - | 524162..525625 (-) | 1464 | WP_000029036.1 | class I SAM-dependent DNA methyltransferase | - |
| AAA985_RS02825 (TKY181970_05530) | - | 525638..527971 (-) | 2334 | WP_000229105.1 | DEAD/DEAH box helicase family protein | - |
| AAA985_RS02830 (TKY181970_05540) | - | 528579..529088 (+) | 510 | Protein_557 | DUF2812 domain-containing protein | - |
| AAA985_RS02835 (TKY181970_05550) | hrcA | 529252..530286 (+) | 1035 | WP_000255781.1 | heat-inducible transcriptional repressor HrcA | - |
| AAA985_RS02840 (TKY181970_05560) | grpE | 530313..530837 (+) | 525 | WP_000046035.1 | nucleotide exchange factor GrpE | - |
| AAA985_RS02845 (TKY181970_05570) | dnaK | 531317..533140 (+) | 1824 | WP_000034662.1 | molecular chaperone DnaK | - |
| AAA985_RS02850 (TKY181970_05580) | - | 533142..533498 (+) | 357 | WP_000114422.1 | hypothetical protein | - |
| AAA985_RS02855 (TKY181970_05590) | dnaJ | 533900..535036 (+) | 1137 | WP_001066301.1 | molecular chaperone DnaJ | - |
| AAA985_RS02860 (TKY181970_05600) | - | 535358..535645 (-) | 288 | WP_000777760.1 | hypothetical protein | - |
| AAA985_RS02865 (TKY181970_05610) | - | 535655..536065 (-) | 411 | WP_001278301.1 | HIT family protein | - |
| AAA985_RS02870 (TKY181970_05620) | pptA | 536133..536864 (+) | 732 | WP_000889919.1 | ABC transporter ATP-binding protein | Regulator |
| AAA985_RS02875 (TKY181970_05630) | - | 536861..537910 (+) | 1050 | WP_000653773.1 | ABC transporter permease | - |
| AAA985_RS02880 (TKY181970_05640) | - | 538078..538407 (-) | 330 | WP_000132572.1 | hypothetical protein | - |
| AAA985_RS02885 (TKY181970_05650) | - | 538683..539021 (+) | 339 | WP_000682126.1 | LytTR family DNA-binding domain-containing protein | - |
| AAA985_RS02890 (TKY181970_05660) | comE/blpR | 539026..539763 (+) | 738 | WP_001219143.1 | response regulator transcription factor | Regulator |
| AAA985_RS02895 (TKY181970_05670) | - | 539777..541117 (+) | 1341 | WP_001028651.1 | sensor histidine kinase | - |
| AAA985_RS02900 (TKY181970_05680) | blpC | 541162..541317 (-) | 156 | WP_000358814.1 | quorum-sensing system pheromone BlpC | - |
| AAA985_RS02905 (TKY181970_05690) | - | 541374..542735 (-) | 1362 | WP_001069081.1 | bacteriocin secretion accessory protein | - |
| AAA985_RS02910 (TKY181970_05700) | - | 542746..544793 (-) | 2048 | Protein_573 | peptide cleavage/export ABC transporter | - |
| AAA985_RS02915 (TKY181970_05720) | blpU | 545074..545304 (+) | 231 | WP_001093268.1 | bacteriocin-like peptide BlpU | - |
| AAA985_RS02920 | - | 545307..545426 (+) | 120 | WP_000346298.1 | PncF family bacteriocin immunity protein | - |
| AAA985_RS02925 (TKY181970_05730) | - | 545723..545887 (+) | 165 | WP_000727118.1 | hypothetical protein | - |
| AAA985_RS02930 (TKY181970_05740) | - | 545884..546288 (+) | 405 | WP_000846944.1 | hypothetical protein | - |
| AAA985_RS02935 | - | 546486..547291 (+) | 806 | Protein_578 | IS5 family transposase | - |
| AAA985_RS02940 (TKY181970_05770) | blpM | 547441..547695 (+) | 255 | WP_000379879.1 | two-peptide bacteriocin subunit BlpM | - |
| AAA985_RS02945 (TKY181970_05780) | blpN | 547711..547914 (+) | 204 | WP_001099492.1 | two-peptide bacteriocin subunit BlpN | - |
| AAA985_RS02950 (TKY181970_05790) | cipB | 548158..548307 (+) | 150 | WP_001813641.1 | bacteriocin-like peptide BlpO | Regulator |
Sequence
Protein
Download Length: 243 a.a. Molecular weight: 27012.49 Da Isoelectric Point: 4.7737
>NTDB_id=105949 AAA985_RS02870 WP_000889919.1 536133..536864(+) (pptA) [Streptococcus pneumoniae strain Pne2]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL
Nucleotide
Download Length: 732 bp
>NTDB_id=105949 AAA985_RS02870 WP_000889919.1 536133..536864(+) (pptA) [Streptococcus pneumoniae strain Pne2]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTTCCTGTTTTGAAAGATGTGTCCTTTACTGTTGAAAGTGG
GCAGTTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCAACGACGATCAATGAGATTATCGGTCTGTTGGCACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACTCTGCAAGGAGATGCGACTAGCTACCGCAAGCAGATTGGCTACATTCCT
GAGACGCCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTACGGTATTGAGCAAAA
AGTGGCTTTCGAACGAGTAGAGCCCTTGTTAAAGATGTTCCGTCTGGACCAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTAGCTATTTCTGATTTGATTCAGCTTTTGGAAGTGGAGAAGCAAAAGGGCAAGTCTATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAGAAGATGTGTGATGCCTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCCAAAG
GCAATCTCCTGCAACTACGCGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACAAAAGAG
GAGGACCTATGA
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTTCCTGTTTTGAAAGATGTGTCCTTTACTGTTGAAAGTGG
GCAGTTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCAACGACGATCAATGAGATTATCGGTCTGTTGGCACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACTCTGCAAGGAGATGCGACTAGCTACCGCAAGCAGATTGGCTACATTCCT
GAGACGCCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTACGGTATTGAGCAAAA
AGTGGCTTTCGAACGAGTAGAGCCCTTGTTAAAGATGTTCCGTCTGGACCAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTAGCTATTTCTGATTTGATTCAGCTTTTGGAAGTGGAGAAGCAAAAGGGCAAGTCTATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAGAAGATGTGTGATGCCTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCCAAAG
GCAATCTCCTGCAACTACGCGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACAAAAGAG
GAGGACCTATGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pptA | Streptococcus salivarius strain HSISS4 |
72.614 |
99.177 |
0.72 |
| pptA | Streptococcus thermophilus LMD-9 |
71.784 |
99.177 |
0.712 |