Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AAA985_RS02305 Genome accession   NZ_AP028603
Coordinates   422640..423329 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain Pne2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 417640..428329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA985_RS02280 (TKY181970_04460) gpsB 417773..418102 (+) 330 WP_000146522.1 cell division regulator GpsB -
  AAA985_RS02290 (TKY181970_04470) - 418588..419745 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  AAA985_RS02295 (TKY181970_04480) mapZ 419758..421128 (+) 1371 WP_000039285.1 mid-cell-anchored protein MapZ -
  AAA985_RS02300 (TKY181970_04490) gndA 421204..422628 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  AAA985_RS02305 (TKY181970_04500) covR 422640..423329 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  AAA985_RS02310 (TKY181970_04510) cbpC 423427..424446 (+) 1020 WP_061369313.1 choline-binding protein CbpC -
  AAA985_RS02315 - 424564..425796 (-) 1233 WP_000765677.1 MFS transporter -
  AAA985_RS02320 (TKY181970_04540) - 425839..426426 (-) 588 WP_001822134.1 lanthionine synthetase LanC family protein -
  AAA985_RS02325 - 426326..426715 (-) 390 WP_001865604.1 lanthionine synthetase LanC family protein -
  AAA985_RS02330 (TKY181970_04550) - 427327..427656 (+) 330 WP_000196972.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=105947 AAA985_RS02305 WP_000518008.1 422640..423329(+) (covR) [Streptococcus pneumoniae strain Pne2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=105947 AAA985_RS02305 WP_000518008.1 422640..423329(+) (covR) [Streptococcus pneumoniae strain Pne2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAACTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment